Endogenous molecules induced by a pathogen-associated molecular pattern (PAMP) elicit innate immunity in shrimp. [PDF]
PLoS ONE, 2014 Invertebrates rely on an innate immune system to combat invading pathogens. The system is initiated in the presence of cell wall components from microbes like lipopolysaccharide (LPS), β-1,3-glucan (βG) and peptidoglycan (PG), altogether known as ...
Yu-Yuan Chen +11 more
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Refractory Behavior in Plant Cells—Calcium Signaling Induced by Biotic Stress [PDF]
PlantsWhen in contact with microbes or other pathogens plants develop an induced defense response. This reaction is triggered by pathogen-derived molecules that provoke the so-called microbe-associated molecular pattern (MAMP)-triggered immunity (MTI) or ...
Mareike Kristin Keßler +3 more
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Regulated expression of pathogen-associated molecular pattern molecules in Staphylococcus epidermidis: quorum-sensing determines pro-inflammatory capacity and production of phenol-soluble modulins. [PDF]
Cellular microbiology, 2004 Phenol-soluble modulin (PSM) is a peptide complex produced by the nosocomial pathogen Staphylococcus epidermidis that has a strong capacity to activate the human innate immune response. We developed a novel method based on liquid chromatography-mass spectrometry (LC-MS) to quantify the production of the individual PSM components.
Cuong, Vuong +5 more
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NLRP3: Role in ischemia/reperfusion injuries
Frontiers in Immunology, 2022 NLR family pyrin domain containing 3 (NLRP3) is expressed in immune cells, especially in dendritic cells and macrophages and acts as a constituent of the inflammasome.
Soudeh Ghafouri-Fard +10 more
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Chromatin-Associated Molecular Patterns (CAMPs) in sepsis
Cell Death and Disease, 2022 Several molecular patterns have been identified that recognize pattern recognition receptors. Pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) are commonly used terminologies to classify molecules ...
Colleen P. Nofi, Ping Wang, Monowar Aziz
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Effect of oestradiol and pathogen‐associated molecular patterns on class II‐mediated antigen presentation and immunomodulatory molecule expression in the mouse female reproductive tract [PDF]
Immunology, 2011 Summary Cells of the female reproductive tract (FRT) can present antigen to naive and memory T cells. However, the effects of oestrogen, known to modulate immune responses, on antigen presentation in the FRT remain undefined.
Daniel O, Ochiel +3 more
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Frontiers in Immunology, 2023 Pattern recognition receptors are primitive sensors that arouse a preconfigured immune response to broad stimuli, including nonself pathogen-associated and autologous damage-associated molecular pattern molecules.
Tian Wang +6 more
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Hyperconservation of the N -Formyl Peptide Binding Site of M3 : Evidence that M3 Is an Old Eutherian Molecule with Conserved Recognition of a Pathogen-Associated Molecular Pattern [PDF]
The Journal of Immunology, 2003 Abstract The mouse MHC class I-b molecule H2-M3 has unique specificity for N-formyl peptides, derived from bacteria (and mitochondria), and is thus a pathogen-associated molecular pattern recognition receptor (PRR). To test whether M3 was selected for this PRR function, we studied M3 sequences from diverse murid species of murine ...
C Kuyler Doyle +4 more
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Post-Translational Modification of HMGB1 Disulfide Bonds in Stimulating and Inhibiting Inflammation
Cells, 2021 High mobility group box 1 protein (HMGB1), a highly conserved nuclear DNA-binding protein, is a “damage-associated molecular pattern” molecule (DAMP) implicated in both stimulating and inhibiting innate immunity.
Ulf Andersson +2 more
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International Journal of Immunopathology and Pharmacology, 2021 Introduction Nucleotide-binding oligomerization domain-like receptor family, pyrin domain containing 3 (NLRP3), an intracellular pattern recognition receptor, recognizes various pathogen-associated molecular pattern and/or damage-associated molecular ...
Wakako Mori +4 more
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