Mitochondria-Derived Damage-Associated Molecular Patterns in Neurodegeneration [PDF]
Frontiers in Immunology, 2017 Inflammation is increasingly implicated in neurodegenerative disease pathology. As no acquired pathogen appears to drive this inflammation, the question of what does remains.
Russell H. Swerdlow +9 more
doaj +3 more sources
Helicobacter pylori Pathogen-Associated Molecular Patterns: Friends or Foes? [PDF]
, 2022 Microbial infections are sensed by the host immune system by recognizing signature molecules called Pathogen-Associated Molecular Patterns—PAMPs. The binding of these biomolecules to innate immune receptors, called Pattern Recognition Receptors (PRRs ...
Amalia Porta +11 more
core +1 more source
Receptor-like kinases and pathogen-associated molecular patterns perception in Arabidopsis [PDF]
, 2006 Comparable to the innate immune response in mammals and insects, plants possess highly specific and sensitive recognition systems for pathogen-associated molecular patterns (PAMPs), such as bacterial flagellin.
Zipfel, Cyril
core +1 more source
Involvement of bacterial TonB-dependent signaling in the generation of an oligogalacturonide damage-associated molecular pattern from plant cell walls exposed to Xanthomonas campestris pv. campestris pectate lyases [PDF]
, 2012 Vorhölter F-J, Wiggerich H-G, Scheidle H, et al. Involvement of bacterial TonB-dependent signaling in the generation of an oligogalacturonide damage-associated molecular pattern from plant cell walls exposed to Xanthomonas campestris pv.
Vishaldeep Kaur Sidhu +24 more
core +2 more sources
Nuclear processes associated with plant immunity and pathogen susceptibility [PDF]
, 2015 Plants are sessile organisms that have evolved exquisite and sophisticated mechanisms to adapt to their biotic and abiotic environment. Plants deploy receptors and vast signalling networks to detect, transmit and respond to a given biotic threat by ...
Kulagina, Natalja +3 more
core +1 more source
Molecular Characteristics of RAGE and Advances in Small-Molecule Inhibitors [PDF]
, 2021 Receptor for advanced glycation end-products (RAGE) is a member of the immunoglobulin superfamily. RAGE binds and mediates cellular responses to a range of DAMPs (damage-associated molecular pattern molecules), such as AGEs, HMGB1, and S100/calgranulins,
Hyeon Jin Kim, Mi Suk Jeong, Se Bok Jang
core +1 more source
Innate Immune Recognition: An Issue More Complex Than Expected
Frontiers in Cellular and Infection Microbiology, 2019 Primary interaction of an intracellular bacterium with its host cell is initiated by activation of multiple signaling pathways in response to bacterium recognition itself or as cellular responses to stress induced by the bacterium.
Klara Kubelkova, Ales Macela
doaj +1 more source
Therapeutic Interventions into Innate Immune Diseases by Means of Aptamers
Pharmaceutics, 2020 The immune system plays a crucial role in the body’s defense system against various pathogens, such as bacteria, viruses, and parasites, as well as recognizes non-self- and self-molecules.
Farzana Yasmeen +4 more
doaj +1 more source
Formin nanoclustering-mediated actin assembly during plant flagellin and DSF signaling
Cell Reports, 2021 Summary: Plants respond to bacterial infection acutely with actin remodeling during plant immune responses. The mechanisms by which bacterial virulence factors (VFs) modulate plant actin polymerization remain enigmatic.
Zhiming Ma +7 more
doaj +1 more source
The role of BRI1-associated kinase 1 (BAK1) in the regulation of plant innate immunity : functional and genetic characterization of BAK1 overexpression in Arabidopsis thaliana [PDF]
, 2014 The role of BRI1-ASSOCIATED KINASE 1 (BAK1) in the regulation of plant innate immunity: functional and genetic characterization of BAK1 overexpression in Arabidopsis thaliana SUMMARY BAK1 (BRI1-ASSOCIATED KINASE 1) is an intensively studied member ...
Kiss-Papp, Márta
core +1 more source