Results 1 to 10 of about 646,259 (330)

Inhibitory pattern recognition receptors [PDF]

Journal of Experimental Medicine, 2021
Pattern recognition receptors (PRRs) activate immune cells upon sensing microbes or tissue damage. To prevent immunopathology, these patterns should not always lead to activation.
Matevž Rumpret, H. V. von Richthofen, V. Peperzak, L. Meyaard   +3 more
semanticscholar   +7 more sources

Pattern recognition receptors and autophagy [PDF]

Frontiers in Immunology, 2014
The immune system senses exogenous threats or endogenous stress through specialized machinery known as pattern recognition receptors (PRRs). These receptors recognize conserved molecular structures and initiate downstream signaling pathways to control ...
Ji Eun eOh, Heung Kyu eLee
doaj   +6 more sources

Pattern recognition receptors in HIV transmission [PDF]

Frontiers in Immunology, 2012
Dendritic cells (DCs), Langerhans cells (LCs) and macrophages are innate immune cells that reside in genital and intestinal mucosal tissues susceptible to HIV-1 infection.
Teunis B. Geijtenbeek, Annelies eMesman
doaj   +5 more sources

Pattern recognition receptors and gastric cancer [PDF]

Frontiers in Immunology, 2014
Chronic inflammation has been associated with an increased risk of several human malignancies, a classic example being gastric cancer (GC). Development of GC is known to result from infection of the gastric mucosa by Helicobacter pylori, which initially ...
Natalia eCastaño-Rodriguez, Nadeem Omar Kaakoush, Hazel Marjory Mitchell   +2 more
doaj   +9 more sources

Effect of human breast milk on innate immune response: Up-regulation of bacterial pattern recognition receptors and innate cytokines in THP-1 monocytic cells

European Journal of Inflammation, 2021
Human breast milk (HBM) contains many bioactive components that protect infants from various microorganisms. Pattern recognition receptors on phagocytic cells recognize microbial pathogens and promote the innate immune system.
Won-Ho Hahn, Soon Young Shin, Jun Hwan Song, Nam Mi Kang   +3 more
doaj   +1 more source

Intracellular PRRs Activation in Targeting the Immune Response Against Fungal Infections

Frontiers in Cellular and Infection Microbiology, 2020
The immune response against fungal infections is complex and exhibits several factors involving innate elements that participate in the interaction with the fungus. The innate immune system developed pattern recognition receptors that recognize different
Grasielle Pereira Jannuzzi, José Roberto Fogaça de Almeida, Larissa Neves Monteiro Paulo, Sandro Rogério de Almeida, Karen Spadari Ferreira   +4 more
doaj   +1 more source

Innate Immunity Crosstalk with Helicobacter pylori: Pattern Recognition Receptors and Cellular Responses

International Journal of Molecular Sciences, 2022
Helicobacter pylori is one of the most successful gastric pathogens that has co-existed with human for centuries. H. pylori is recognized by the host immune system through human pattern recognition receptors (PRRs), such as toll-like receptors (TLRs), C ...
Y. Y. Cheok, Grace Min Yi Tan, C. Lee, Suhailah Abdullah, C. Looi, W. Wong   +5 more
semanticscholar   +1 more source

Nature's soothing solution: Harnessing the potential of food-derived polysaccharides to control inflammation

Current Research in Structural Biology, 2023
Reducing inflammation by diet is a major goal for prevention or lowering symptoms of a variety of diseases, such as auto-immune reactions and cancers.
Lucas de Freitas Pedrosa, Paul de Vos, João Paulo Fabi   +2 more
doaj   +1 more source

Pattern-recognition receptors are required for NLR-mediated plant immunity

Nature, 2020
The plant immune system is fundamental for plant survival in natural ecosystems and for productivity in crop fields. Substantial evidence supports the prevailing notion that plants possess a two-tiered innate immune system, called pattern-triggered ...
Minhang Yuan, Zeyu Jiang, Guozhi Bi, K. Nomura, Menghui Liu, Yiping Wang, Boying Cai, Jian‐Min Zhou, S. He, Xiu-Fang Xin   +9 more
semanticscholar   +1 more source

Comparative genome analysis reveals an absence of leucine-rich repeat pattern-recognition receptor proteins in the kingdom Fungi.

PLoS ONE, 2010
BackgroundIn plants and animals innate immunity is the first line of defence against attack by microbial pathogens. Specific molecular features of bacteria and fungi are recognised by pattern recognition receptors that have extracellular domains ...
Darren M Soanes, Nicholas J Talbot
doaj   +1 more source