Results 1 to 10 of about 398,630 (257)

Pattern recognition receptors in antifungal immunity [PDF]

Seminars in Immunopathology, 2014
We thank the Wellcome Trust for funding this study.Peer reviewedPublisher ...
Brown, Gordon D, Hardison, Sarah E, Plato, Anthony   +2 more
core   +5 more sources

The phylogenetically-related pattern recognition receptors EFR and XA21 recruit similar immune signaling components in monocots and dicots [PDF]

, 2015
During plant immunity, surface-localized pattern recognition receptors (PRRs) recognize pathogen-associated molecular patterns (PAMPs). The transfer of PRRs between plant species is a promising strategy for engineering broad-spectrum disease resistance ...
A Afroz, A Farid, A Heese, AP Macho, B Schulze, B Schwessinger, BBH Wulff, BMJ Mendes, C Dardick, C Dardick, C Zipfel, CJ Park, CJ Park, CJ Park, CJ Park, CR Buell, Cyril Zipfel, D Chinchilla, DP Lu, DP Lu, EF Fradin, FG da Silva, FG Malinovsky, H Haweker, J Li, J Santiago, J Zhang, JL Dangl, JM Gagne, JM Gagne, JR Wan, K Bouwmeester, K Yamaguchi, L Gomez-Gomez, L Li, LA Boyd, LL Gao, M Albert, M Roux, MD Lehti-Shiu, MD Lehti-Shiu, N Tintor, Nicholas Holton, O Bahar, P Tang, Pamela C. Ronald, RC Edgar, S Burdman, S Lacombe, S Robatzek, SG Hwang, SH Shiu, SH Shiu, SH Shiu, SK Song, SM Chaw, T Boller, T Halter, T Sakamoto, V Nekrasov, Vladimir Nekrasov, W Lin, Wenbo Ma, WQ Zeng, WY Song, X Chen, X Lu, XF Xin, Y Kadota, Y Kawano, Y Shen, Y Sun, YD Sun, YJ Zan, YN Jiang, YS Wang, ZX Liu   +76 more
core   +15 more sources

The influence of CpG and UpA dinucleotide frequencies on RNA virus replication and characterization of the innate cellular pathways underlying virus attenuation and enhanced replication [PDF]

, 2014
Most RNA viruses infecting mammals and other vertebrates show profound suppression of CpG and UpA dinucleotide frequencies. To investigate this functionally, mutants of the picornavirus, echovirus 7 (E7), were constructed with altered CpG and UpA ...
Atkinson, Nicky J., Evans, David J., Simmonds, Peter, Witteveldt, Jeroen   +3 more
core   +2 more sources

Pattern recognition receptors as key players in adrenal gland dysfunction during sepsis [PDF]

, 2012
Background: Undergoing systemic inflammation, the innate immune system releases excessive proinflammatory mediators, which finally can lead to organ failure. Pattern recognition receptors (PRRs), such as Toll-like receptors (TLRs) and NOD-like receptors (
Bornstein, Stefan R., Hoesker, Vanessa, Kanczkowski, Waldemar, Tran, Thi Hoai Nguyen, Zacharowski, Kai   +4 more
core   +1 more source

High levels of cyclic-di-GMP in plant-associated Pseudomonas correlate with evasion of plant immunity [PDF]

, 2016
The plant innate immune system employs plasma membrane-localized receptors that specifically perceive pathogen/microbe-associated molecular patterns (PAMPs/MAMPs).
Aragon, Barahona, Baraquet, Berendsen, Boller, Burdette, Cao, Chinchilla, Clarke, Dangl, Dasgupta, Dong, Engl, Felix, Forsyth, Gal, Gomez-Gomez, Goymer, Guttman, Hann, Heese, Hengge, Hickman, Hickman, Jackson, Kazmierczak, Kovach, Kulasakara, Kunze, Lacombe, Lee, Li, Loon, Loper, Loper, Lugtenberg, Macho, Malone, Marino, Matilla, Miya, Newell, Nuhse, Peart, Pel, Perez-Mendoza, Plotnikova, Robleto, Rossez, Roux, Schulze, Schwessinger, Segonzac, Spangler, Starkey, Sun, Torres, Van Wees, Wang, Willmann, Winsor, Xin, Yan, Zamioudis, Zeng, Zhang, Zipfel, Zipfel, Zipfel   +68 more
core   +1 more source

Domain architecture evolution of pattern-recognition receptors [PDF]

, 2010
In animals, the innate immune system is the first line of defense against invading microorganisms, and the pattern-recognition receptors (PRRs) are the key components of this system, detecting microbial invasion and initiating innate immune defenses. Two
Qing Zhang, Christian M. Zmasek, Adam Godzik, SF Altschul, G Apic, NA Baker, MK Basu, A Bateman, B Beutler, TA Binkowski, AK Bjorklund, D Boraschi, CB Burge, AA Canutescu, RR Copley, JA Darling, R Desper, M Dlugosz, CB Do, SR Eddy, J Felsenstein, K Forslund, JH Fritz, O Gascuel, J Gough, JH Han, T Hibino, AL Hughes, AL Hughes, A Ishii, Z Kambris, TD Kanneganti, K Katoh, KJ Laing, O Lespinet, F Leulier, A Marchler-Bauer, A Marchler-Bauer, F Martinon, AF McGettrick, R Medzhitov, PA Nuin, LA O'Neill, H Oshiumi, L Patthy, K Pawlowski, NH Putnam, NH Putnam, H Qin, AJ Robertson, F Ronquist, L Sael, N Saitou, JM Sasin, HA Schmidt, E Sodergren, A Stamatakis, C Stein, JP Ting, J Weiner 3rd, AP West, MJ West-Eberhard, Q Zhang   +62 more
core   +2 more sources

Identification of CNS Injury-Related microRNAs as Novel Toll-Like Receptor 7/8 Signaling Activators by Small RNA Sequencing [PDF]

, 2020
Toll-like receptors (TLRs) belong to pattern recognition receptors, which respond to danger signals such as pathogen-associated molecular patterns or damage-associated molecular patterns.
Buonfiglioli, Alice, Dembny, Paul, Krüger, Christina, Lehnardt, Seija, Prinz, Marco, Staszewski, Ori, Wallach, Thomas, Wetzel, Max   +7 more
core   +1 more source

Interaction between Cannabinoid System and Toll-Like Receptors Controls Inflammation [PDF]

, 2016
Since the discovery of the endocannabinoid system consisting of cannabinoid receptors, endogenous ligands, and biosynthetic and metabolizing enzymes, interest has been renewed in investigating the promise of cannabinoids as therapeutic agents.
McCoy, Kathleen L.
core   +4 more sources

PRRDB: A comprehensive database of Pattern-Recognition Receptors and their ligands [PDF]

, 2008
Background Recently in a number of studies, it has been demonstrated that the innate immune system doesn't merely acts as the first line of defense but provides critical signals for the development of specific adaptive immune response.
Sneh Lata, Gajendra Raghava
core   +1 more source

Inflammation-induced DNA damage and damage-induced inflammation: a vicious cycle [PDF]

, 2014
Inflammation is the ultimate response to the constant challenges of the immune system by microbes, irritants or injury. The inflammatory cascade initiates with the recognition of microorganism-derived pathogen associated molecular patterns (PAMPs) and ...
Abe, Alexeyev, Andersson, Andersson, Ba, Babior, Bartoloni, Berger, Blyth, Brill, Brinkmann, Cadet, Collins, Cooke, Csanád Z. Bachrati, David, Ding, Dostert, Ermakov, Ermakov, Ferguson, Fuchs, Gahan, Gedik, Gehrke, Hajizadeh, Halle, Hiramoto, Huang, Huang, Huang, Huttunen, Ishikawa, Ivana, Ivanov, Jahr, Jia, Kang, Kanneganti, Kazak, Klebanoff, Knaapen, Kondo, Kostyuk, Kostyuk, Krieg, Kuechle, Lane, Lange, Latz, Li, Malins, Mariathasan, Munoz-Gamez, Nakahira, Oka, Pacher, Parvatiyar, Pasheva, Pinti, Polk, Rathinam, Saitoh, Saxena, Scaffidi, Schroder, Shimada, Shokolenko, Sun, Suter, Suzuki, Swindall, Tadie, Taguchi, Takeda, Takeda, Tang, Tang, Thomson, Timea Pálmai-Pallag, Unterholzner, Urbonaviciute, Venereau, Volcic, Weinberg, Weiss, Wilson, Wu, Yan, Yang, Yoshida, Yoshihara, Yotsumoto, You, Yousefi, Zhang, Zhang, Zhang, Zhang, Zhang, Zhou   +100 more
core   +1 more source