Results 21 to 30 of about 646,259 (330)

Inherited variation in pattern recognition receptors and cancer: dangerous liaisons? [PDF]

Cancer Management and Research, 2012
Anton G Kutikhin, Arseniy E YuzhalinDepartment of Epidemiology, Kemerovo State Medical Academy, Kemerovo, Russian FederationAbstract: The group of pattern recognition receptors includes families of Toll-like receptors, NOD-like receptors, C-type lectin ...
Yuzhalin AE, Kutikhin AG
doaj   +1 more source

Primary immunodeficiencies of pattern recognition receptors [PDF]

Journal of Internal Medicine, 2012
AbstractPrimary immunodeficiencies (PIDs) are severe defects in the capacity of the host to mount a proper immune response, and are characterized by an increased susceptibility to infections. Although classical immunodeficiencies have been characterized based on broad defects in cell populations (e.g.
Netea, M.G., van de Veerdonk, F.L., Meer, J.W.M. van der   +2 more
openaire   +5 more sources

Pattern-recognition Receptors in Pulp Defense [PDF]

Advances in Dental Research, 2011
Initial sensing of infection is mediated by germline-encoded pattern-recognition receptors (PRRs), the activation of which leads to the expression of inflammatory mediators responsible for the elimination of pathogens and infected cells. PRRs act as immune sensors that provide immediate cell responses to pathogen invasion or tissue injury.
M-J, Staquet, F, Carrouel, J-F, Keller, C, Baudouin, P, Msika, F, Bleicher, T A, Kufer, J-C, Farges   +7 more
openaire   +3 more sources

NKp44 and Natural Cytotoxicity Receptors as Damage Associated Molecular Pattern Recognition Receptors [PDF]

Frontiers in Immunology, 2015
Natural Killer (NK) cells are a key constituent of the innate immune system, protecting against bacteria, virally infected cells, and cancer. Recognition and protective function against such cells is dictated by activating and inhibitory receptors on ...
Porunelloor Abraham Mathew, Nathan Chad Horton   +1 more
doaj   +2 more sources

Pattern Recognition Receptors and the Host Cell Death Molecular Machinery

Frontiers in Immunology, 2018
Pattern Recognition Receptors (PRRs) are proteins capable of recognizing molecules frequently found in pathogens (the so-called Pathogen-Associated Molecular Patterns—PAMPs), or molecules released by damaged cells (the Damage-Associated Molecular ...
Gustavo P. Amarante-Mendes, Gustavo P. Amarante-Mendes, Sandy Adjemian, Sandy Adjemian, Laura Migliari Branco, Laura Migliari Branco, Larissa C. Zanetti, Ricardo Weinlich, Karina R. Bortoluci, Karina R. Bortoluci   +9 more
doaj   +2 more sources

PRRDB: A comprehensive database of Pattern-Recognition Receptors and their ligands [PDF]

BMC Genomics, 2008
Background Recently in a number of studies, it has been demonstrated that the innate immune system doesn't merely acts as the first line of defense but provides critical signals for the development of specific adaptive immune response.
Lata Sneh, Raghava Gajendra
doaj   +3 more sources

Bacterial and Fungal Pattern Recognition Receptors in Homologous Innate Signaling Pathways of Insects and Mammals [PDF]

Frontiers in Microbiology, 2015
In response to bacterial and fungal infections in insects and mammals, distinct families of innate immune pattern recognition receptors initiate highly complex intracellular signaling cascades.
Bethany A Stokes, Shruti eYadav, Upasana eShokal, L Courtney Smith, Ioannis eEleftherianos   +4 more
doaj   +2 more sources

Pattern recognition receptors in GtoPdb v.2021.3 [PDF]

, 2021
Pattern Recognition Receptors (PRRs, [104]) (nomenclature as agreed by NC-IUPHAR sub-committee on Pattern Recognition Receptors, [18]) participate in the innate immune response to microbial agents, the stimulation of which leads to activation of ...
Bryant, Clare, Monie, Tom P.
core   +2 more sources

Identifying the Patterns of Pattern Recognition Receptors [PDF]

Immunity, 2018
Intestinal homeostasis requires microbial recognition that results in appropriate responses to commensals and pathogens. In this issue of Immunity, Price et al. (2018) map the in vivo expression of five toll-like receptors (TLR) in intestinal epithelia, revealing distinct spatio-temporal expression patterns that shape responses to TLR ligands.
Andrea A, Hill, Gretchen E, Diehl
openaire   +2 more sources

Pattern recognition receptors in GtoPdb v.2023.1 [PDF]

, 2023
Pattern Recognition Receptors (PRRs, [110]) (nomenclature as agreed by NC-IUPHAR sub-committee on Pattern Recognition Receptors, [20]) participate in the innate immune response to microbial agents, the stimulation of which leads to activation of ...
Clare Bryant, Bryant, Clare, Tom P. Monie, Monie, Tom P.   +3 more
core   +2 more sources