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Pattern Recognition Receptors and Inflammation [PDF]
Cell, 2010 Infection of cells by microorganisms activates the inflammatory response. The initial sensing of infection is mediated by innate pattern recognition receptors (PRRs), which include Toll-like receptors, RIG-I-like receptors, NOD-like receptors, and C-type lectin receptors.
Takeuchi, Osamu, Akira, Shizuo
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Are Pattern Recognition Receptors Associated with Hepatocellular Carcinoma?
The Turkish Journal of Gastroenterology, 2021 Background: Hepatocellular carcinoma (HCC) is one of the important causes of mortality due to malignancy. Toll-like receptors (TLRs) are very important in liver pathophysiology in terms of their roles in the innate immune system, such as the regulation ...
Ramazan Dertli +7 more
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European Journal of Inflammation, 2021 Human breast milk (HBM) contains many bioactive components that protect infants from various microorganisms. Pattern recognition receptors on phagocytic cells recognize microbial pathogens and promote the innate immune system.
Won-Ho Hahn +3 more
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Intracellular PRRs Activation in Targeting the Immune Response Against Fungal Infections
Frontiers in Cellular and Infection Microbiology, 2020 The immune response against fungal infections is complex and exhibits several factors involving innate elements that participate in the interaction with the fungus. The innate immune system developed pattern recognition receptors that recognize different
Grasielle Pereira Jannuzzi +4 more
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Immune functions of pattern recognition receptors in Lepidoptera
Frontiers in Immunology, 2023 Pattern recognition receptors (PRRs), as the “sensors” in the immune response, play a prominent role in recognizing pathogen-associated molecular patterns (PAMPs) and initiating an effective defense response to pathogens in Lepidoptera.
Lin Zhao +4 more
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Current Research in Structural Biology, 2023 Reducing inflammation by diet is a major goal for prevention or lowering symptoms of a variety of diseases, such as auto-immune reactions and cancers.
Lucas de Freitas Pedrosa +2 more
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PLoS ONE, 2010 BackgroundIn plants and animals innate immunity is the first line of defence against attack by microbial pathogens. Specific molecular features of bacteria and fungi are recognised by pattern recognition receptors that have extracellular domains ...
Darren M Soanes, Nicholas J Talbot
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Frontiers in Immunology, 2023 Pattern recognition receptors are primitive sensors that arouse a preconfigured immune response to broad stimuli, including nonself pathogen-associated and autologous damage-associated molecular pattern molecules.
Tian Wang +6 more
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Role of pattern recognition receptors in sensing Mycobacterium tuberculosis
Heliyon, 2023 Mycobacterium tuberculosis is one of the major invasive intracellular pathogens causing most deaths by a single infectious agent. The interaction between host immune cells and this pathogen is the focal point of the disease, Tuberculosis.
S.M. Neamul Kabir Zihad +7 more
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Nature Communications, 2022 The detection of conserved motifs by pattern recognition receptors is a crucial component of the innate detection of pathogens and danger signals via conserved pattern recognition receptors.
Catherine J. Greene +12 more
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