Results 41 to 50 of about 646,259 (330)

"Open Sesame" to the complexity of pattern recognition receptors of myeloid-derived suppressor cells in cancer

Frontiers in Immunology, 2023
Pattern recognition receptors are primitive sensors that arouse a preconfigured immune response to broad stimuli, including nonself pathogen-associated and autologous damage-associated molecular pattern molecules.
Tian Wang, Yushu Hu, Silvia Dusi, Fang Qi, Silvia Sartoris, Stefano Ugel, Francesco De Sanctis   +6 more
doaj   +1 more source

Role of pattern recognition receptors in sensing Mycobacterium tuberculosis

Heliyon, 2023
Mycobacterium tuberculosis is one of the major invasive intracellular pathogens causing most deaths by a single infectious agent. The interaction between host immune cells and this pathogen is the focal point of the disease, Tuberculosis.
S.M. Neamul Kabir Zihad, Nazifa Sifat, Mohammad Ashraful Islam, A.S.M. Monjur-Al-Hossain, K.M. Yasif Kayes Sikdar, Md Moklesur Rahman Sarker, Jamil A. Shilpi, Shaikh Jamal Uddin   +7 more
doaj   +1 more source

Macrophages disseminate pathogen associated molecular patterns through the direct extracellular release of the soluble content of their phagolysosomes

Nature Communications, 2022
The detection of conserved motifs by pattern recognition receptors is a crucial component of the innate detection of pathogens and danger signals via conserved pattern recognition receptors.
Catherine J. Greene, Jenny A. Nguyen, Samuel M. Cheung, Corey R. Arnold, Dale R. Balce, Ya Ting Wang, Adrian Soderholm, Neil McKenna, Devin Aggarwal, Rhiannon I. Campden, Benjamin W. Ewanchuk, Herbert W. Virgin, Robin M. Yates   +12 more
doaj   +1 more source

Recognition of human oncogenic viruses by host pattern recognition receptors

Frontiers in Immunology, 2014
Human oncogenic viruses include Epstein-Barr virus (EBV), hepatitis B virus (HBV), hepatitis C virus (HCV), human papilloma virus (HPV), human T-cell lymphotropic virus (HTLV-1), Kaposi’s associated sarcoma virus (KSHV), and Merkel cell polyomavirus ...
Nelson C Di Paolo
doaj   +1 more source

Genotyping-by-sequencing-based identification of Arabidopsis pattern recognition receptor RLP32 recognizing proteobacterial translation initiation factor IF1

Nature Communications, 2022
Pattern-triggered immunity is activated by recognition of microbe-derived structures by host pattern recognition receptors. Here the authors use a genotype-by sequencing approach to show that bacterial translation initiation factor 1 triggers PTI in ...
Li Fan, Katja Fröhlich, Eric Melzer, Rory N. Pruitt, Isabell Albert, Lisha Zhang, Anna Joe, Chenlei Hua, Yanyue Song, Markus Albert, Sang-Tae Kim, Detlef Weigel, Cyril Zipfel, Eunyoung Chae, Andrea A. Gust, Thorsten Nürnberger   +15 more
doaj   +1 more source

Intracellular pattern-recognition receptors☆

Advanced Drug Delivery Reviews, 2008
The last ten years of research in the field of innate immunity have been incredibly fertile: the transmembrane Toll-like receptors (TLRs) were discovered as guardians protecting the host against microbial attacks and the emerging pathways characterized in detail.
DOSTERT, C, Meylan, Etienne, Tschopp, J
openaire   +4 more sources

Pattern recognitions receptors in immunodeficiency disorders [PDF]

European Journal of Pharmacology, 2017
Pattern recognition receptors (PRRs) recognize common microbial or host-derived macromolecules and have important roles in early activation and response of the immune system. Initiation of the innate immune response starts with the recognition of microbial structures called pathogen associated molecular patterns (PAMPs).
Mortaz, E, Adcock, IM, Tabarsi, P, Darazam, IA, Movassaghi, M, Garssen, J, Jamaati, H, Velayati, A   +7 more
openaire   +4 more sources

Interaction Between Virus-Like Particles (VLPs) and Pattern Recognition Receptors (PRRs) From Dendritic Cells (DCs): Toward Better Engineering of VLPs

Frontiers in Immunology, 2020
Virus-like particles (VLPs) have been shown to be strong activators of dendritic cells (DCs). DCs are the most potent antigen presenting cells (APCs) and their activation prompts the priming of immunity mediators based on B and T cells.
Jesús Zepeda-Cervantes, J. O. Ramírez-Jarquín, L. Vaca   +2 more
semanticscholar   +1 more source

Gram-positive bacterial lipoglycans based on a glycosylated diacylglycerol lipid anchor are microbe-associated molecular patterns recognized by TLR2 [PDF]

, 2013
Innate immune recognition is the first line of host defense against invading microorganisms. It is a based on the detection, by pattern recognition receptors (PRRs), of invariant molecular signatures that are unique to microorganisms.
Alain Vercellone, Nigou, Jerome, Iain Sutcliffe, Besra, Gurdyal, Mishra Arun K., Arun K Mishra, Jérôme Nigou, Blanc Landry, Sutcliffe Iain, Mishra, Arun, Gurdyal S Besra, Castanier Romain, Ray, Aurélie, Romain Castanier, Vercellone, Alain, Ray Aurélie, Mishra, Arun K, Castanier, Romain, Landry Blanc, Blanc, Landry, Vercellone Alain, Nigou Jérôme, Besra, Gurdyal S; id_orcid, Sutcliffe, Iain, Besra Gurdyal S., Mishra, Arun K., Aurélie Ray   +26 more
core   +1 more source

Pattern‐recognition receptors in human eosinophils [PDF]

Immunology, 2012
SummaryThe pattern‐recognition receptor (PRR) family includes Toll‐like receptors (TLRs), nucleotide‐binding oligomerization domain (NOD) ‐like receptors (NLRs), RIG‐I‐like receptors (RLRs), C‐type lectin receptors (CLRs) and the receptor for advanced glycation end products (RAGE).
Anne Månsson, Kvarnhammar, Lars Olaf, Cardell   +1 more
openaire   +2 more sources