Results 11 to 20 of about 646,259 (330)
Pattern recognition receptors in health and diseases [PDF]
Signal Transduction and Targeted Therapy, 2021 Pattern recognition receptors (PRRs) are a class of receptors that can directly recognize the specific molecular structures on the surface of pathogens, apoptotic host cells, and damaged senescent cells.
Danyang Li, Minghua Wu
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Evolutionary trajectory of pattern recognition receptors in plants
Nature Communications, 2023 Cell-surface receptors play pivotal roles in many biological processes, including immunity, development, and reproduction, across diverse organisms. How cell-surface receptors evolve to become specialised in different biological processes remains elusive.
Bruno Pok Man Ngou +4 more
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Pattern recognition receptors and inflammation. [PDF]
Cell, 2010 Infection of cells by microorganisms activates the inflammatory response. The initial sensing of infection is mediated by innate pattern recognition receptors (PRRs), which include Toll-like receptors, RIG-I-like receptors, NOD-like receptors, and C-type lectin receptors.
O. Takeuchi, S. Akira
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Pattern recognition receptors in fungal immunity [PDF]
Seminars in Cell & Developmental Biology, 2019 Highlights • Growing list of PRRs that sense pathogenic fungal conserved moieties.• Enhanced immune responses or fungal evasion mechanisms occur through PRR crosstalk.• Increasing evidence of potent inhibitory mechanisms during PRR signalling.• PRR ...
E. Patin, A. Thompson, Selinda J. Orr
semanticscholar +5 more sources
Immune functions of pattern recognition receptors in Lepidoptera
Frontiers in Immunology, 2023 Pattern recognition receptors (PRRs), as the “sensors” in the immune response, play a prominent role in recognizing pathogen-associated molecular patterns (PAMPs) and initiating an effective defense response to pathogens in Lepidoptera.
Lin Zhao +4 more
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cGLRs are a diverse family of pattern recognition receptors in innate immunity
Cell, 2023 Summary cGAS (cyclic GMP-AMP synthase) is an enzyme in human cells that controls an immune response to cytosolic DNA. Upon binding DNA, cGAS synthesizes a nucleotide signal 2′3′-cGAMP that activates STING-dependent downstream immunity.
Philip J Kranzusch
exaly +2 more sources
Pattern recognition receptors in microbial keratitis [PDF]
Eye, 2015 Microbial keratitis is a significant cause of global visual impairment and blindness. Corneal infection can be caused by a wide variety of pathogens, each of which exhibits a range of mechanisms by which the immune system is activated. The complexity of the immune response to corneal infection is only now beginning to be elucidated.
Taube, M.A. +4 more
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Natural Cytotoxicity Receptors: Pattern Recognition and Involvement of Carbohydrates
The Scientific World Journal, 2005 Natural cytotoxicity receptors (NCRs), expressed by natural killer (NK) cells, trigger NK lysis of tumor and virus-infected cells on interaction with cell-surface ligands of these target cells.
Angel Porgador
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Pattern recognition receptors: function, regulation and therapeutic potential
Signal Transduction and Targeted TherapyPattern recognition receptors (PRRs) are sensors in the immune system, detecting pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs).
Ruochan Chen +5 more
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Pattern Recognition Receptors [PDF]
Cell, 2002 Antigen presenting cells (macrophages and dendritic cells) express pattern recognition molecules that are thought to recognize foreign ligands during early phases of the immune response. The best known of these are probably the Toll-like receptors, but a
Gordon, Siamon, Siamon Gordon
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