Results 31 to 40 of about 118,779 (271)
, 2012 Vorhölter F-J, Wiggerich H-G, Scheidle H, et al. Involvement of bacterial TonB-dependent signaling in the generation of an oligogalacturonide damage-associated molecular pattern from plant cell walls exposed to Xanthomonas campestris pv.
Vishaldeep Kaur Sidhu +24 more
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Identification of receptor complex components and receptor activation mechanisms in plant innate immunity [PDF]
, 2011 Plants rely on an innate immune system which successfully recognizes and restricts pathogenic microbes. The key for this defense is the detection of pathogen derived non-self signatures and endogenous elicitors released during a microbial attack.
Mentzel, Tobias
core +1 more source
Molecular Characteristics of RAGE and Advances in Small-Molecule Inhibitors
, 2021 Receptor for advanced glycation end-products (RAGE) is a member of the immunoglobulin superfamily. RAGE binds and mediates cellular responses to a range of DAMPs (damage-associated molecular pattern molecules), such as AGEs, HMGB1, and S100/calgranulins,
Hyeon Jin Kim, Mi Suk Jeong, Se Bok Jang
core +1 more source
The role of toll-like receptors in peptic ulcer disease
Immunological Medicine, 2021 Helicobacter pylori (HP) is the primary etiologic factor that induces events in the immune system that lead to peptic ulcers. Toll-like receptors (TLRs) are an important part of the innate immune system, as they play pivotal roles in pathogen-associated ...
Shizhu Jin, Narayan Nepal, Yang Gao
doaj +1 more source
Nuclear Alarmin Cytokines in Inflammation
Journal of Immunology Research, 2020 Pathogen-associated molecular patterns (PAMPs) are some nonspecific and highly conserved molecular structures of exogenous specific microbial pathogens, whose products can be recognized by pattern recognition receptor (PRR) on innate immune cells and ...
Lili Jiang +4 more
doaj +1 more source
Cell Death-Associated Molecular-Pattern Molecules: Inflammatory Signaling and Control [PDF]
, 2014 Apoptosis, necroptosis, and pyroptosis are different cellular death programs characterized in organs and tissues as consequence of microbes infection, cell stress, injury, and chemotherapeutics exposure.
Nancy Marcela Pérez +3 more
core +1 more source
Toll-Interacting Protein in Resolving and Non-Resolving Inflammation
Frontiers in Immunology, 2017 Innate leukocytes manifest dynamic and distinct inflammatory responses upon challenges with rising dosages of pathogen-associated molecular pattern molecules such as lipopolysaccharide (LPS).
Elizabeth J. A. Kowalski, Liwu Li
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Extracellular HMGB1: a therapeutic target in severe pulmonary inflammation including COVID-19?
Molecular Medicine, 2020 Background The 2019 novel coronavirus disease (COVID-19) causes for unresolved reasons acute respiratory distress syndrome in vulnerable individuals. There is a need to identify key pathogenic molecules in COVID-19-associated inflammation attainable to ...
Ulf Andersson +2 more
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The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli +3 more
wiley +1 more source
Immune functions of pattern recognition receptors in Lepidoptera
Frontiers in Immunology, 2023 Pattern recognition receptors (PRRs), as the “sensors” in the immune response, play a prominent role in recognizing pathogen-associated molecular patterns (PAMPs) and initiating an effective defense response to pathogens in Lepidoptera.
Lin Zhao +4 more
doaj +1 more source