Results 51 to 60 of about 118,779 (271)

Uncovering the Mechanisms: The Role of Biotrophic Fungi in Activating or Suppressing Plant Defense Responses

Journal of Fungi
This paper discusses the mechanisms by which fungi manipulate plant physiology and suppress plant defense responses by producing effectors that can target various host proteins.
Michel Leiva-Mora, Yanelis Capdesuñer, Ariel Villalobos-Olivera, Roberto Moya-Jiménez, Luis Rodrigo Saa, Marcos Edel Martínez-Montero   +5 more
doaj   +1 more source

Deubiquitinases: Novel Therapeutic Targets in Immune Surveillance?

Mediators of Inflammation, 2016
Inflammation is a protective response of the organism to tissue injury or infection. It occurs when the immune system recognizes Pathogen-Associated Molecular Patterns (PAMPs) or Damage-Associated Molecular Pattern (DAMPs) through the activation of ...
Gloria Lopez-Castejon, Mariola J. Edelmann   +1 more
doaj   +1 more source

The molecular pathways underlying host resistance and tolerance to pathogens

Frontiers in Genetics, 2012
Breeding livestock that are better able to withstand the onslaught of endemic and exotic pathogens is high on the wish list of breeders and farmers world-wide.
Elizabeth Janet Glass
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Role of Toll-Like Receptor Signaling in the Progression of Heart Failure

Mediators of Inflammation, 2018
Medical systems worldwide are being faced with a growing need to understand mechanisms behind the pathogenesis of heart failure (HF) that is considered as a leading cause of morbidity and mortality around the world.
Lili Yu, Zhiwei Feng
doaj   +1 more source

The grateful dead: damage-associated molecular pattern molecules and reduction/oxidation regulate immunity

, 2007
The response to pathogens and damage in plants and animals involves a series of carefully orchestrated, highly evolved, molecular mechanisms resulting in pathogen resistance and wound healing.
Lotze, Michael T., Sparvero, L.J., Michael E. DeVera, Timothy Billiar, Louis J. Sparvero, Lotze, M.T., Washburn, Newell R., Amoscato, Andrew A., Zeh, Herbert J., Toer, Mahmut, Newell R. Washburn, Zeh, H.J., Rubartelli, A., Billiar, T., Anna Rubartelli, Amoscata, A.A., Mahmut Tör, Tör, M., Liang, Xiaoyan, Andrew A. Amoscato, Washburn, N.R., Sparvero, Louis J., Billiar, Timothy, Rubartelli, Anna, Liang, X., Herbert J. Zeh, Michael T. Lotze, Xiaoyan Liang, DeVera, Michael E., Devera, M.E.   +29 more
core   +1 more source

Loss of susceptibility as a novel breeding strategy for durable and broad-spectrum resistance [PDF]

, 2010
Recent studies on plant immunity have suggested that a pathogen should suppress induced plant defense in order to infect a plant species, which otherwise would have been a nonhost to the pathogen. For this purpose, pathogens exploit effector molecules to
Visser, R.G.F., JACOBSEN E, VISSER RGF, Jacobsen, E., Pavan, S.N.C., Bai, Y., BAI Y., PAVAN, STEFANO   +7 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Pathogens and Dead Cells Cooperate with Cytokines in Activating the Innate and Adaptive Response

European Journal of Inflammation, 2011
After microbial invasion and tissue damage, a set of cytokines, including interleukin-1α (IL-1α), IL-1β, IL-6, IL-18 and tumor necrosis factor-α (TNF-α), and microbial and endogenous molecules named pathogen-associated molecular pattern (PAMPs) and ...
J.E. Belizário
doaj   +1 more source

Evolution of MHC diversity in cetacean species environment: implications for the role of a pathogen [PDF]

, 2004
Previous studies have indicated that the evolution of diversity in the immune system genes responsible for antigen presentation in terrestrial mammals is driven by selection.
Vassilakos, Demetrios
core