Abstract Rheumatoid arthritis (RA) is a chronic, highly disabling autoimmune disease. Although modern medical treatments have made progress, challenges such as suboptimal efficacy, relapse, difficulties in comorbidity management, and side effects persist.
Dier Jin +8 more
wiley +1 more source
Identification of neutralizing nanobodies protecting against poxvirus infection
An outbreak of mpox has triggered concerns regarding the adequacy of intervention strategies. Passive immunity conferred by neutralizing antibodies exhibits potential in the prophylaxis and treatment of orthopoxvirus infections.
Xuehua Yang +15 more
doaj +1 more source
The Coexistence of Pathogens and Pseudomonads in Soluble Oil Emulsions
R. Samuel-Maharajah +3 more
openalex +1 more source
NOTCH2NLC Repeat Expansions in Parkinsonian Disorders: Clinical and Neuroimaging Characteristics
ABSTRACT Objective Neuronal intranuclear inclusion disease (NIID) is a neurodegenerative disorder caused by NOTCH2NLC GGC repeat expansions, with heterogeneous clinical manifestations, including parkinsonism. Recent studies have identified NOTCH2NLC repeat expansions in patients with Parkinson's disease (PD) and atypical parkinsonism (aPM), suggesting ...
Han‐Lin Chiang +7 more
wiley +1 more source
Safe Procedure for Opening Evacuated Glass Ampoules Containing Dried Pathogens [PDF]
Donald Greiff
openalex +2 more sources
Survival of wound pathogens under different environmental conditions [PDF]
Felicity Pettit, E. J. L. Lowbury
openalex +1 more source
Central Dysmyelination in SSADH‐Deficient Humans and Mice
ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer +11 more
wiley +1 more source
Observations on the reactions of plant to the infection of some pathogens.
T. Mizukami
openalex +2 more sources
THE ROLE OF COMPLEMENT IN RESISTANCE TO ENDOGENOUS AND EXOGENOUS INFECTION WITH A COMMON MOUSE PATHOGEN, CORYNEBACTERIUM KUTSCHERI [PDF]
Linda D. Caren, Leon T. Rosenberg
openalex +1 more source
Long‐Term Evaluation of Givinostat in Duchenne Muscular Dystrophy, and Natural History Comparisons
ABSTRACT Objectives This ongoing, open‐label extension study is evaluating the long‐term safety, tolerability, and efficacy of givinostat, a Class I and II histone deacetylase inhibitor, in patients with Duchenne muscular dystrophy (DMD). Methods The recruited patients completed one of two prior clinical studies (one Phase 2 and one Phase 3 [EPIDYS ...
Craig M. McDonald +74 more
wiley +1 more source

