Results 41 to 50 of about 1,693,186 (355)

Identification of the BolA Protein Reveals a Novel Virulence Factor in K. pneumoniae That Contributes to Survival in Host

Microbiology Spectrum, 2022
BolA has been characterized as an important transcriptional regulator, which is induced in the stationary phase of growth and is often associated with bacterial virulence.
Feiyang Zhang, Xiangjin Yan, Jiawei Bai, Li Xiang, Manlin Ding, Qin Li, Biying Zhang, Qinghua Liang, Yingshun Zhou   +8 more
doaj   +1 more source

SjTat-TPI facilitates adaptive T-cell responses and reduces hepatic pathology during Schistosoma japonicum infection in BALB/c mice

Parasites & Vectors, 2015
Background Schistosomiasis is a kind of parasitic zoonoses which causes serious damage to public health and social development. China is one of the countries most affected by Schistosoma japonicum and an effective vaccine is still needed.
Wenyue Zhang, Xiaofeng Luo, Fan Zhang, Yuxiao Zhu, Bingya Yang, Min Hou, Zhipeng Xu, Chuanxin Yu, Yingying Chen, Lin Chen, Minjun Ji   +10 more
doaj   +1 more source

The pathogenicity of cytomegalovirus [PDF]

FEMS Microbiology Reviews, 1999
Human cytomegalovirus is ubiquitous, yet causes little illness in immunocompetent individuals. Disease is evident in immunodeficient groups such as neonates, transplant recipients and AIDS patients either following a primary infection or reactivation of a latent infection. Little is known of the mechanisms underlying the pathogenicity of the virus. The
openaire   +3 more sources

Molecular and physiological characterization of the chitin synthase B gene isolated from Culex pipiens pallens (Diptera: Culicidae)

Parasites & Vectors, 2019
Background The growth and development of insects is strictly dependent on the precise regulation of chitin synthase (CHS), which is absent in vertebrates and plants. Therefore, CHS represents an attractive target for insecticides.
Xiaoshan Yang, Qi Yin, Yang Xu, Xixi Li, Yan Sun, Lei Ma, Dan Zhou, Bo Shen   +7 more
doaj   +1 more source

NYD-OP7/PLC regulatory signaling pathway regulates deltamethrin resistance in Culex pipiens pallens (Diptera: Culicidae)

Parasites & Vectors, 2018
Background Investigation of insecticide resistance mechanisms is considered a vital first step towards the creation of effective strategies to control resistant mosquitoes and manage mosquito-borne diseases.
Dan Zhou, Baiyun Duan, Yang Xu, Lei Ma, Bo Shen, Yan Sun, Changliang Zhu   +6 more
doaj   +1 more source

Pathogen Sensors [PDF]

Sensors, 2009
The development of sensors for detecting foodborne pathogens has been motivated by the need to produce safe foods and to provide better healthcare. However, in the more recent times, these needs have been expanded to encompass issues relating to biosecurity, detection of plant and soil pathogens, microbial communities, and the environment. The range of
openaire   +3 more sources

Elevated serum antibody against Schistosoma japonicum HSP60 as a promising biomarker for liver pathology in schistosomiasis

Scientific Reports, 2017
The pathology associated with Schistosoma japonicum (S. japonicum) infection in humans is attributed to parasite egg-induced granulomatous inflammation and fibrosis in the host liver.
Xiaojun Chen, Wei Li, Yalin Li, Lei Xu, Sha Zhou, Jifeng Zhu, Zhipeng Xu, Feng Liu, Dandan Lin, Fei Hu, Yuemin Liu, Wen Jiang, Liwang Cui, Chuan Su   +13 more
doaj   +1 more source

Schistosoma japonicum infection causes a reprogramming of glycolipid metabolism in the liver

Parasites & Vectors, 2019
Background Recent investigations indicate that schistosome infection is closely associated with aberrant glycolipid metabolism. However, the actual glycolipid metabolism gene expression, as well as the possible pathways that regulate glycolipid ...
Zhi-Peng Xu, Hao Chang, Yang-Yue Ni, Chen Li, Lin Chen, Min Hou, Min-Jun Ji   +6 more
doaj   +1 more source

Genetic diversity of Plasmodium vivax populations from the China–Myanmar border identified by genotyping merozoite surface protein markers

Tropical Medicine and Health, 2023
Background Parasite diversity and population structure influence malaria control measures. Malaria transmission at international borders affects indigenous residents and migrants, defying management efforts and resulting in malaria re-introduction.
Xun Wang, Yao Bai, Zheng Xiang, Weilin Zeng, Yanrui Wu, Hui Zhao, Wei Zhao, Xi Chen, Mengxi Duan, Xiaosong Li, Wenya Zhu, Kemin Sun, Yiman Wu, Yanmei Zhang, Xiaomei Li, Benjamin M. Rosenthal, Liwang Cui, Zhaoqing Yang   +17 more
doaj   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source