Results 111 to 120 of about 720,916 (356)

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

The potential of volatile organic compound analysis for pathogen detection and disease monitoring in patients with cystic fibrosis

, 2022
Anton Barucha, Renan Marrichi Mauch, Franziska Duckstein, Carlos Zagoya, Jochen G. Mainz   +4 more
openalex   +2 more sources

Surveillance for Early Detection of High-Consequence Pests and Pathogens [PDF]

, 2022
John H. Bowers, Jerry R. Malayer, Beatriz Martínez‐López, Joseph LaForest, Charles T. Bargeron, Alison D. Neeley, Leonard B. Coop, Brittany S. Barker, Alexander Mastin, Stephen Parnell, Allard A. Cossé, Brian J. McCluskey, Scott A. Isard, Joseph M. Russo   +13 more
openalex   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Tickborne Pathogen Detection, Western Siberia, Russia

Emerging Infectious Diseases, 2005
Ixodes persulcatus (n = 125) and Dermacentor reticulatus (n = 84) ticks from Western Siberia, Russia, were tested for infection with Borrelia, Anaplasma/Ehrlichia, Bartonella, and Babesia spp. by using nested polymerase chain reaction assays with subsequent sequencing. I. persulcatus ticks were infected with Borrelia burgdorferi sensu lato (37.6% +/- 4.
Vera A. Rar, Natalia V. Fomenko, Andrey K. Dobrotvorsky, Natalya N. Livanova, Svetlana A. Rudakova, Evgeniy G. Fedorov, Vadim B. Astanin, Olga V. Morozova   +7 more
openaire   +3 more sources

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Establishment and Application of Loop-Mediated Isothermal Amplification Assays for Pathogens of Rice Bakanae Disease

Agriculture
Rice bakanae disease (RBD), a major threat in rice-cropping nations, can reduce rice yield and quality. As it is a seed-borne disease, effective seed detection is crucial. Loop-mediated isothermal amplification (LAMP) can rapidly and specifically amplify
Xinchun Liu, Yan Wang, Yating Zhang, Jingzhao Xia, Chenxi Liu, Yu Song, Tao Han, Songhong Wei, Wenjing Zheng   +8 more
doaj   +1 more source

Using Museum Collections to Detect Pathogens

Emerging Infectious Diseases, 2009
À l'éditeur : Les collections des musées d'histoire naturelle ont évolué ces dernières années pour répondre aux défis des études scientifiques interdisciplinaires actuelles et futures. De nombreux musées d'histoire naturelle ont constitué des collections de tissus et mis à disposition gratuitement sur Internet des informations numériques (par exemple ...
C. Miguel Pinto, B. Dnate' Baxter, John D. Hanson, Francisca M. Méndez-Harclerode, John R. Suchecki, Mario J. Grijalva, Charles F. Fulhorst, Robert D. Bradley   +7 more
openaire   +3 more sources