Results 71 to 80 of about 3,727,441 (314)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Genetic characterization of type 3 vaccine-derived poliovirus from a patient with hand, foot, and mouth disease in China

Virology Journal
Background The Oral Polio Vaccine (OPV) is genetically unstable and may mutate to form vaccinederived polioviruses (VDPVs). At present, the finding of VDPV mainly come from AFP surveillance and environmental sewage surveillance.
Wei Zhang, Dongmei Yan, Hanri Zeng, Lei Zhou, Huanying Zheng, Shuangli Zhu, Yong Zhang, Baisheng Li   +7 more
doaj   +1 more source

Broad range molecular detection methods identify only Borrelia spp. in erythema migrans biopsies and blood of tick-bitten patients

One Health
In this multicenter study conducted in France, we challenged the hypothesis of the transmission of pathogens other than Borrelia spp. in 22 patients developing erythema migrans following a tick bite.
Philippe Pérot, Laura Tondeur, Sara Moutailler, Delphine Chrétien, Nicole Corre-Catelin, Muriel Vayssier-Taussat, Marc Eloit, Catherine Chirouze, Céline Cazorla, Laurence Arowas, Elisabeth Botelho-Nevers, Céline Cazorla, Catherine Chirouze, Delphine Chrétien, Nicole Corre-Catelin, Marc Eloit, Pascale Frey-Klett, Arnaud Fontanet, Clémence Galon, Karine Lacombe, Sara Moutailler, Philippe Pérot, Véronique Perronne, Valentine Piquard, Marie Préau, Costanza Puppo, Laura Tondeur, Marie-Noelle Ungeheuer, Muriel Vayssier-Taussat, Ayla Zayoud   +29 more
doaj   +1 more source

Electrochemical biosensors for pathogen detection

Biosensors and Bioelectronics, 2020
Recent advances in electrochemical biosensors for pathogen detection are reviewed. Electrochemical biosensors for pathogen detection are broadly reviewed in terms of transduction elements, biorecognition elements, electrochemical techniques, and biosensor performance.
Cesewski, Ellen, Johnson, Blake N.
openaire   +2 more sources

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Electrical Detection of Pneumococcus through the Nanoparticle Decoration Method

Sensors, 2017
A simple method of nanoparticle decoration can be used in the detection of pneumococcus. After the pneumococcal bacteria were captured by an antibody (pneumococcal C-polysaccharide (PnC) antibody) between the interdigitated electrodes, the gold ...
Hannah Pyo, Cho Yeon Lee, Daehee Kim, Gyuhee Kim, Sangho Lee, Wan Soo Yun   +5 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Electrochemical biosensors for rapid pathogen detection

, 2021
Rapid pathogen detection is an emerging issue in clinical, environmental, and food industry sectors. Biosensors can represent a solution to culture-based and molecular methods as they respond to sensitivity, specificity, and rapidity needs.
Manzano, Marisa, Vidic, Jasmina, Marisa Manzano, Jasmina Vidic   +3 more
core   +1 more source

Phage-based biosensors for pathogen detection

Biocontaminant
Pathogenic bacteria continue to pose a severe and persistent threat to global public health, necessitating the development of rapid, sensitive, and reliable detection systems.
Wei Wang, Yuanyuan Xue, Zihan Xu, Mao Lin, Qingshun Guo, Li Cui   +5 more
doaj   +1 more source