Results 81 to 90 of about 3,727,441 (314)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Transcriptome of citrus and citrus relatives for pathogen detection

, 2021
Transcriptome of citrus and citrus relatives for pathogen detection Please add these files to SUB9101535 (Bioproject # PRJNA704425)
USDA (17854931)
core  

Research Progress of Near-Infrared Fluorescence Immunoassay

Micromachines, 2019
Near-infrared fluorescence probes (NIFPs) have been widely used in immunoassay, bio-imaging and medical diagnosis. We review the basic principles of near-infrared fluorescence and near-infrared detection technology, and summarize structures, properties ...
Xiao-Hui Chang, Jie Zhang, Lin-Huan Wu, Yan-Kun Peng, Xiang-Ying Yang, Xiao-Lin Li, Ai-Jin Ma, Jun-Cai Ma, Guang-Quan Chen   +8 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Two Years after Coxiella burnetii Detection: Pathogen Shedding and Phase-Specific Antibody Response in Three Dairy Goat Herds

, 2023
The infection dynamics of Coxiella (C.) burnetii were investigated in three dairy goat herds (A, B, and C) 2 years after the first pathogen detection. A total of 28 and 29 goats from herds A and B, and 35 goats from herd C, were examined.
Trachsel, Christa
core  

jodyphelan/host-pathogen: Host-pathogen-code v1.0

, 2023
Code required for host-pathogen ...
Jody Phelan
core   +1 more source

Expanding Horizons in Advancements of FRET Biosensing Technologies

Biosensors
Förster resonance energy transfer (FRET)-based biosensors are versatile tools for obtaining insights into various biological processes. Their working principles are based on nonradiative energy transfer from donor to acceptor fluorophores.
Munazza Fatima, Naseem Abbas
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

CRISPR-Cas-based techniques for pathogen detection: Retrospect, recent advances, and future perspectives

, 2023
Background: Early detection of pathogen-associated diseases are critical for effective treatment. Rapid, specific, sensitive, and cost-effective diagnostic technologies continue to be challenging to develop.
Rui Zhang, Jinming Li, Tao Huang
core   +1 more source

Respiratory pathogen detection and Co-detection in hospitalized children with lower respiratory tract infections using multiplex RT-qPCR: A single-center retrospective Observational Study

Therapeutic Advances in Infectious Disease
Background Lower respiratory tract infections (LRTIs) are a common cause of pediatric hospitalization, but distinguishing viral from bacterial etiologies based solely on clinical findings remains challenging. Multiplex real-time polymerase chain reaction
Yunus Nas, Süveyda Gözüküçük, Bekir Sami Uyanık, Basri Çakıroğlu   +3 more
doaj   +1 more source