Results 61 to 70 of about 3,853,988 (234)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Options for dust reduction from poultry houses [PDF]

, 2009
Large poultry houses emit high amounts of fine dust (PM10) and in many cases they exceed the ambient air quality standard set by the EU. Technologies for PM10 reduction need to be developed on short term to minimize PM10 emissions from poultry houses ...
de Buisonjé, F.E., Harn, J., van, Winkel, A., Aarnink, A.J.A., van Harn, J., Cambra-López, M., Mosquera, J., Buisonjé, F.E., de, Ogink, N.W.M.   +8 more
core  

Harm reduction among injecting drug users - evidence of effectiveness [PDF]

, 2010
This chapter synthesises and evaluates the available direct evidence relating to the impact of needle and syringe programmes (NSPs), opioid substitution treatment (OST), drug consumption rooms (DCRs), and peer naloxone distribution (PND) on HIV/hepatitis
Hutchinson, Sharon, Kimber, Jo, Palmateer, Norah, Goldberg, David, Rhodes, Tim, Hickman, Matthew   +5 more
core   +2 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Pathogen transmission from vaccinated hosts can cause dose-dependent reduction in virulence.

PLoS Biology, 2020
Many livestock and human vaccines are leaky because they block symptoms but do not prevent infection or onward transmission. This leakiness is concerning because it increases vaccination coverage required to prevent disease spread and can promote ...
Richard I Bailey, Hans H Cheng, Margo Chase-Topping, Jody K Mays, Osvaldo Anacleto, John R Dunn, Andrea Doeschl-Wilson   +6 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

FIELD EVALUATION OF CERTAIN INSECTICIDES AND INSECT PATHOGEN NEMATODE AGAINST ZEUZERA PYRINA (LINNUAEUS) (LEPIDOPTERA: COSSIDAE) INFESTED OLIVE TREES IN NORTH SINAI, EGYPT

Journal of Productivity and Development, 2008
Field experiments were conducted on Zeuzera pyrina L. infested olive trees at El-Arish, North Sinai for three successive years 2002, 2003 and 2004 to evaluate the effects of insecticides and insect pathogen against this pest.
Hasan Nabil, Waheed Desuky, Abd El Menyem Hassan, Aly El-Sheakh   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Genome sequence of the necrotrophic plant pathogen Pythium ultimum reveals original pathogenicity mechanisms and effector repertoire [PDF]

, 2010
Background: Pythium ultimum (P. ultimum) is a ubiquitous oomycete plant pathogen responsible for a variety of diseases on a broad range of crop and ornamental species. Results: The P.
Beakes, Gordon W, Lévesque, CA, Cano, L., Puiu, D, Ronald P De Vries, Raffaele, Sylvain, Hostetler, Jessica, Henrissat, B., Paul D Thomas, Phuntmart, Vipaporn, Boore, J.L., Brett R Whitty, Beakes, GW, Whitty, Brett R, Grenville-Briggs, L., Whitty, Brett R., Horner, N, Cano, L, Raffaele, S., Robideau, Gregg P, Steve Ferriera, Tisserat, Ned, Shetty, J, Tisserat, N., Busam, D, Krajaejun, T., Stajich, JE, Holt, C, Yandell, M, Zerillo, MM, C Robin Buell, West, Pieter van, Morris, P., Hamilton, John P, Pedro M Coutinho, Buell, C. Robin, Martin, Frank, Wawra, S, Whitty, B.R., Sucheta Tripathy, Meijer, Harold J. G., Thines, Marco, Buell, C.R., Wawra, Stephan, Win, J, Gregg P Robideau, Gordon W Beakes, Gachon, Claire M. M., Henk Brouwer, Gachon, C.M.M., Ned Tisserat, Susan I Fuerstenberg, Whitty, BR, Busam, Dana, Phuntmart, V., Thomas, P.D., Govers, F, Mark Yandell, Hostetler, J, Marcelo M Zerillo, Gachon, Claire MM, Lévesque, C.A., Neil Horner, Beakes, G.W., Tisserat, N, Dana Busam, Dumas, B., Yandell, M., Horner, Neil, Krajaejun, T, Zerillo, M.M., Joe Win, Edgar Huitema, Tyler, Brett M., Robideau, G.P., Zerillo, M., Zerillo, Marcelo M, Grenville-Briggs, L, Krajaejun, Theerapong, Raffaele, S, Vries, Ronald Peter de, Johnson, J, Theerapong Krajaejun, Coutinho, Pedro, M, Lévesque, C André, Yandell, Mark, Govers, F., Vries, R.P., de, van West, Pieter, Rays HY Jiang, Puiu, Daniela, Boore, JL, Beakes, Gordon W., De Vries, Ronald P., Coutinho, P.M., Gaulin, Elodie, Win, J., Barry Moore, van West, P, Meijer, H.J.G., Meijer, HJG, Lin, H., Wawra, S., Lin, H, Jessica Hostetler, Paul Morris, Lévesque, C. André, Stephan Wawra, Sylvain Raffaele, Laura Grenville-Briggs, Fuerstenberg, S.I., Bernard Dumas, Meijer, Harold JG, Shetty, J., Phuntmart, V, De Vries, R.P., Tripathy, S, Coutinho, Pedro M., Gachon, Claire M M, Moore, B, Thines, M, Claire MM Gachon, Fuerstenberg, SI, Robideau, Gregg P., Henrissat, Bernard, Dumas, B, Huitema, Edgar; id_orcid, Brouwer, Henk, Grenville-Briggs, Laura, Moore, Barry, Hostetler, J., Huitema, E., Liliana Cano, Puiu, D., Coutinho, Pedro,, Hamilton, J.P., Ferriera, Steve, Zerillo, Marcelo M., Marco Thines, Daniela Puiu, Huitema, E, Sophien Kamoun, Henrissat, B, Boore, Jeffrey L., Jiang, Rays HY, Stajich, Jason E, De Vries, Ronald P, Bernard Henrissat, van West, P., Kamoun, Sophien, Gaulin, E, Brouwer, H., Win, Joe, Gaulin, E., West, P., van, Huitema, Edgar, Brouwer, H, Justin Johnson, Jiang, Rays H. Y., Thines, M., Jyoti Shetty, Tripathy, S., Frank Martin, Tyler, Brett M, Buell, C Robin, Jiang, RHY, Buell, CR, Morris, Paul, Govers, Francine, Tyler, B.M., Jason E Stajich, Ferriera, S, Jiang, R.H.Y., John P Hamilton, Martin, F, Meijer, Harold J G, Kamoun, S., Jiang, Rays H Y, Brett M Tyler, Fürstenberg, Susan, Hamilton, John P., Lin, Haining, Horner, N., Elodie Gaulin, Thomas, Paul D, Haining Lin, Robideau, GP, Coutinho, PM, Johnson, Justin, Tyler, BM, Harold JG Meijer, Francine Govers, Fuerstenberg, Susan I, Cano, Liliana, Vipaporn Phuntmart, Stajich, J.E., Moore, B., Holt, Carson, Thomas, Paul D., Holt, C., Hamilton, JP, Gachon, CMM, Shetty, Jyoti, Stajich, Jason E., Carson Holt, Jeffrey L Boore, Coutinho, Pedro M, Martin, F., Boore, Jeffrey L, De Vries, RP, Johnson, J., Pieter van West, Morris, P, Thomas, PD, C André Lévesque, Fuerstenberg, Susan I., Dumas, Bernard, Ferriera, S., Tripathy, Sucheta, Kamoun, S, Busam, D.   +220 more
core   +1 more source

Evaluation of Mirasol pathogen reduction system by artificially contaminating platelet concentrates with Staphylococcus epidermidis: A pilot study from India

Asian Journal of Transfusion Science, 2016
Background and Objectives: This study was conducted to assess the efficacy of Mirasol pathogen reduction system for platelets aimed at preventing bacterial regrowth by spiking buffy coat pooled platelets (BCPP) with clinically relevant load of ...
Kabita Chatterjee, Shamsuz Zaman, Rahul Chaurasia, Surinder Singh, Shawn D Keil, Shalini Tewari, Akanksha Bisht, Nitin Agarwal, Diptiranjan Rout, Subhash Chand, Kallol Saha   +10 more
doaj   +1 more source