Results 91 to 100 of about 11,620,757 (255)
Pathogen genomic surveillance status among lower resource settings in Asia [PDF]
Asia remains vulnerable to new and emerging infectious diseases. Understanding how to improve next generation sequencing (NGS) use in pathogen surveillance is an urgent priority for regional health security.
Wulandari, Suci +3 more
core +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Nanopore Sequencing Technology: A Reliable Method for Pathogen Diagnosis in Elderly Patients with Community-Acquired Pneumonia [PDF]
Xiyue Zhang,1,* Jian Ye,2,* Limin Wang,1 Liuhai Zhang,1 Liusheng Wang,1 Hualiang Jin1 1Department of Respiratory Medicine, Affiliated Hangzhou First People’s Hospital, School of Medicine, Westlake University, Hangzhou, People’s Republic of China;
Jin H, Zhang X, Zhang L, Ye J, Wang L
core
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Bacterial contamination of platelet products in the Blood Transfusion Center of Isfahan, Iran
GMS Hygiene and Infection Control, 2016 Aim: Overall the risk of transfusion transmitted infections has decreased, especially viral infections like HIV and hepatitis B and C. Bacterial contamination of blood and its cellular components, however, remains a common microbiological cause of ...
Farzad, Baghi Baghban +4 more
doaj +1 more source
Improvement of Blood Processing and Safety by Automation and Pathogen Reduction Technology. [PDF]
Transfus Med Hemother, 2021 Pérez Aliaga AI +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Impact of pathogen reduction technology on neutralizing antibody titer in COVID-19 convalescent plasma. [PDF]
Transfus Clin Biol, 2022 Franchini M +6 more
europepmc +1 more source
Protecting plants against the fungal pathogen Sclerotinia sclerotiorum using host-induced gene silencing [PDF]
Sclerotinia sclerotiorum is a fungal pathogen that affects Canadian crops every year. Brassica napus (canola) is particularly vulnerable. Chemical fungicides are widely used to control S. sclerotiorum.
Caners, Rhey
core
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source