Results 81 to 90 of about 11,620,757 (255)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Operational integration of pulsed xenon UV disinfection systems in high-throughput logistics networks

AIP Advances
This study introduces a novel conveyor-integrated pulsed xenon ultraviolet system to address microbial contamination risks in logistics networks. The technology combines automated parcel rotation, multi-axis UV emitter arrays, and broadband emission (200–
Chenwei Dai, Yong Xu, Kai Liu, Yiyan Yu, Qinghua Xu, Yu Bai   +5 more
doaj   +1 more source

Technology Architectural Review [PDF]

, 1887
Publication of the Massachusetts Institute of Technology Architectural Society. Volume 3.
Massachusetts Institute of Technology. Department of Architecture, Massachusetts Institute of Technology. Architectural Society   +1 more
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Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Pathogen reduction in human plasma treated with Riboflavin and UV light: impact on coagulation factor VIII

Zdravniški Vestnik, 2012
Background: Pathogen reduction system is expected to effectively reduce pathogen load of blood components while simultaneously maintaining the quality of cells and proteins.
Ana Milojković, Marko Cukjati, Dragoslav Domanović   +2 more
doaj  

Power Ultrasound and Organic Acid-Based Hurdle Technology to Reduce Listeria monocytogenes and Salmonella enterica on Fresh Produce

Microbiology Research
The increasing demand for fresh fruits and vegetables has been accompanied by a rise in foodborne illness outbreaks linked to fresh produce. Traditional antimicrobial washing treatments, such as chlorine and peroxyacetic acid, have limitations in ...
Megan L. Fay, Priya Biswas, Xinyi Zhou, Bashayer A. Khouja, Diana S. Stewart, Catherine W. Y. Wong, Wei Zhang, Joelle K. Salazar   +7 more
doaj   +1 more source

Photohydroionization Reduces Shiga Toxin-Producing Escherichia coli and Salmonella on Fresh Beef with Minimal Effects on Meat Quality

Meat and Muscle Biology, 2019
The photohydroionization (PHI) technology utilizes a combination of UV light and low-level oxidizers to produce antimicrobial action, and thus, is a potential intervention to control pathogen contamination on surface of fresh beef.
Keith E. Belk, Norasak Kalchayanand, Tommy Wheeler, Xiang Yang   +3 more
doaj   +2 more sources

Genetically programmable pathogen sense and destroy/ [PDF]

, 2012
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biological Engineering, 2012.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Cataloged from
Gupta, Saurabh, Ph. D. Massachusetts Institute of Technology. Dept. of Biological Engineering
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