Results 71 to 80 of about 1,837,939 (209)

Identification of Different Classes of Luminal Progenitor Cells within Prostate Tumors

open access: yesCell Reports, 2015
Primary prostate cancer almost always has a luminal phenotype. However, little is known about the stem/progenitor properties of transformed cells within tumors.
Supreet Agarwal   +14 more
doaj   +1 more source

Candida glabrata: A Lot More Than Meets the Eye

open access: yesMicroorganisms, 2019
Candida glabrata is an opportunistic human fungal pathogen that causes superficial mucosal and life-threatening bloodstream infections in individuals with a compromised immune system. Evolutionarily, it is closer to the non-pathogenic yeast Saccharomyces
Kundan Kumar   +3 more
doaj   +1 more source

PATHOGENESIS OF ENDOMETRIOSIS

open access: yesObstetrics and Gynecology Clinics of North America, 1997
This article reviews the pathogenesis of endometriosis, which involves retrograde dissemination of endometrium and/or development in situ by metaplasia, and there is evidence suggesting that genetic and hormonal factors may play a role. There is also substantial evidence that immunologic factors, namely peritoneal macrophages, T cells, natural killer ...
E, Oral, A, Arici
openaire   +2 more sources

Pathogenesis of Alzheimer′s disease

open access: yes, 2007
Russell H SwerdlowDepartment of Neurology, University of Virginia School of Medicine, Charlottesville, VA, USAAbstract: Alzheimer’s disease (AD) is incredibly common. Increasing longevity ensures its prevalence will rise even further.
Russell H Swerdlow
core  

Pathogenesis of Nephrolithiasis [PDF]

open access: yesJournal of Urology, 2013
Much has been learned in the last decade regarding the initial steps of crystal deposition and ultimate stone formation. There appear to be 3 basic pathways for crystal formation in the upper urinary tract. The first and most common pathway is the overgrowth of calcium oxalate on suburothelial deposits of hydroxyapatite, so-called Randall plaque.1 This
openaire   +2 more sources

Role of the chemokine receptors CCR1, CCR2 and CCR4 in the pathogenesis of experimental dengue infection in mice [PDF]

open access: yes, 2010
Dengue virus (DENV), a mosquito-borne flavivirus, is a public health problem in many tropical countries. Recent clinical data have shown an association between levels of different chemokines in plasma and severity of dengue.
Mauro M Teixeira   +30 more
core   +2 more sources

Research Progress on Antivirulence Agents Targeting the Accessory Gene Regulator (Agr) System of Staphylococcus Aureus

open access: yesInfection and Drug Resistance
Lingwei Chen,1,2 Mintao Huang,1,2 Ying Chen,1,2 Yanzhen Lin,1,2 Yanguang Cong1– 4 1Dongguan Key Laboratory for Pathogenesis and Experimental Diagnosis of Infectious Diseases, The First Dongguan Affiliated Hospital, School of Medical Technology, Guangdong
Chen L, Huang M, Chen Y, Lin Y, Cong Y
doaj  

Structure-Based Drug Designing Recommends HDAC6 Inhibitors To Attenuate Microtubule-Associated Tau-Pathogenesis

open access: yes, 2018
Protein acetylation and deacetylation play vital roles in the structural and physiological behavior of target proteins. Histone deacetylase 6 (HDAC6) remains a key therapeutic target in several chronic diseases such as cancer, neurodegenerative, and ...
Shailima Rampogu (3856018)   +5 more
core   +1 more source

Bacterial Virulence Factors that Contribute to Periodontal Pathogenesis

open access: yes, 2017
In this chapter, the role of different microbial virulence factors in relation to the pathogenesis of periodontal diseases is addressed. These factors are molecules produced by pathogens and contribute to their pathogenicity by promoting colonization and
Gunnar Dahlén   +4 more
core   +1 more source

A Chimeric Peptide Derived from a Bacterial Effector Protein Attenuates TLR-2/4-Mediated Production of Pro-Inflammatory Cytokines and Enhances the Cellular Availability of Gentamicin

open access: yesJournal of Inflammation Research
Binita Roy Nandi,1,2 Biswaranjan Patra,1,2 Girish K Radhakrishnan1 1Laboratory of Bacterial Pathogenesis, National Institute of Animal Biotechnology, Hyderabad, Telangana, 500032, India; 2Regional Centre for Biotechnology (RCB), Faridabad, 121001 ...
Nandi BR, Patra B, Radhakrishnan GK
doaj  

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