Results 1 to 10 of about 262,088 (310)

Research Progresses on the Function and Detection Methods of Insect Gut Microbes

Microorganisms, 2023
The insect gut is home to an extensive array of microbes that play a crucial role in the digestion and absorption of nutrients, as well as in the protection against pathogenic microorganisms.
Yazi Li, Liyun Chang, Ke Xu, Shuhong Zhang, Fengju Gao, Yongshan Fan   +5 more
doaj   +1 more source

Preparation of Monoclonal Antibody against Deoxynivalenol and Development of Immunoassays

Toxins, 2022
Fusarium toxins are the largest group of mycotoxins, which contain more than 140 known secondary metabolites of fungi. Deoxynivalenol (DON) is one of the most important compounds of this class due to its high toxicity and its potential to harm mankind ...
Hoyda Elsir Mokhtar, Aidi Xu, Yang Xu, Mohamed Hassan Fadlalla, Shihua Wang   +4 more
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Genetic Interaction of Global Regulators AflatfA and AflatfB Mediating Development, Stress Response and Aflatoxins B1 Production in Aspergillus flavus

Toxins, 2022
Aspergillus flavus produces carcinogenic and mutagenic aflatoxins, which cause economic losses and risk of food safety by contaminating grains, food and feed.
Xiuna Wang, Wenjie Zha, Bin Yao, Lan Yang, Shihua Wang   +4 more
doaj   +1 more source

The membrane mucin Msb2 regulates aflatoxin biosynthesis and pathogenicity in fungus Aspergillus flavus

Microbial Biotechnology, 2021
Summary As a pathogenic fungus, Aspergillus flavus can produce carcinogenic aflatoxins (AFs), which poses a great threat to crops and animals. Msb2, the signalling mucin protein, is a part of mitogen‐activated protein kinase (MAPK) pathway which ...
Ling Qin, Ding Li, Jiaru Zhao, Guang Yang, Yinchun Wang, Kunlong Yang, Elisabeth Tumukunde, Shihua Wang, Jun Yuan   +8 more
doaj   +1 more source

The Fungi-specific histone Acetyltransferase Rtt109 mediates morphogenesis, Aflatoxin synthesis and pathogenicity in Aspergillus flavus by acetylating H3K9

IMA Fungus, 2021
Aspergillus flavus is a common saprophytic filamentous fungus that produces the highly toxic natural compound aflatoxin during its growth process. Synthesis of the aflatoxins, which can contaminate food crops causing huge losses to the agricultural ...
Ruilin Sun, Meifang Wen, Lianghuan Wu, Huahui Lan, Jun Yuan, Shihua Wang   +5 more
doaj   +1 more source

Development of Immunochromatographic Strip for Detection of αB-VxXXIVA-Conotoxin Based on 5E4 Monoclonal Antibody

Toxins, 2022
Given the application of αB-VxXXIVA-conotoxin (αB-CTX) in analgesics and cancer chemotherapeutics, and its threat to humans, it is urgent to develop a rapid, effective and accurate method for the analysis and detection of αB-CTX in real shellfish and ...
Hengkun Tang, Haimei Liu, Rui Chen, Yehong Gao, Mingke Dong, Sumei Ling, Rongzhi Wang, Shihua Wang   +7 more
doaj   +1 more source

The bZIP Transcription Factor AflRsmA Regulates Aflatoxin B₁ Biosynthesis, Oxidative Stress Response and Sclerotium Formation in Aspergillus flavus

Toxins, 2020
Fungal secondary metabolites play important roles not only in fungal ecology but also in humans living as beneficial medicine or harmful toxins. In filamentous fungi, bZIP-type transcription factors (TFs) are associated with the proteins involved in ...
Xiuna Wang, Wenjie Zha, Linlin Liang, Opemipo Esther Fasoyin, Lihan Wu, Shihua Wang   +5 more
doaj   +1 more source

GTPase Rac Regulates Conidiation, AFB1 Production and Stress Response in Pathogenic Fungus Aspergillus flavus

Toxins, 2022
As a member of the Rho family, Rac plays important roles in many species, including proliferation, differentiation, apoptosis, DNA damage responses, metabolism, angiogenesis, and immunosuppression.
Ling Qin, Lan Yang, Jiaru Zhao, Wanlin Zeng, Minxuan Su, Shihua Wang, Jun Yuan   +6 more
doaj   +1 more source

Detection of αB-Conotoxin VxXXIVA (αB-CTX) by ic-ELISA Based on an Epitope-Specific Monoclonal Antibody

Toxins, 2022
In view of the toxicological hazard and important applications in analgesics and cancer chemotherapeutics of αB-CTX, it is urgent to develop an accurate, effective and feasible immunoassay for the determination and analysis of αB-CTX in real samples.
Hengkun Tang, Haimei Liu, Yehong Gao, Rui Chen, Mingke Dong, Sumei Ling, Rongzhi Wang, Shihua Wang   +7 more
doaj   +1 more source

aflN Is Involved in the Biosynthesis of Aflatoxin and Conidiation in Aspergillus flavus

Toxins, 2021
Aspergillus flavus poses a threat to society economy and public health due to aflatoxin production. aflN is a gene located in the aflatoxin gene cluster, but the function of AflN is undefined in Aspergillus flavus.
Kunzhi Jia, Lijuan Yan, Yipu Jia, Shuting Xu, Zhaoqi Yan, Shihua Wang   +5 more
doaj   +1 more source