Results 171 to 180 of about 244,283 (268)

<i>DhSip1</i>, an NRPS-independent siderophore biosynthetic gene, regulates adhesive knob formation and pathogenicity in <i>Dactylellina haptotyla</i> through mediating iron acquisition. [PDF]

Appl Environ Microbiol
Lei H-M, Shen S-M, Xu P, Li G-H, Zhao P-J.   +4 more
europepmc   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

Bioprospection of entomopathogenic fungi natives of Brazilian Semi-arid with potential for biological control of Insect-pests. [PDF]

World J Microbiol Biotechnol
Santos TS, de Almeida Santos JF, Santos ELT, Santos TS, Leite JLS, Blank AF, Mendonça MDC.   +6 more
europepmc   +1 more source

Hydrogel Microtube Drug Carrier for Catheter‐Based Intravascular Therapy

Advanced Healthcare Materials, EarlyView.
This paper proposes hydrogel microtube carriers composed of barium alginate gel, enabling long‐term vascular retention without interrupting blood flow. Intravascular treatments have long been attracting attention for therapeutic efficacy, yet practical delivery methods remained unestablished.
Shota Sato, Hiroki Ohta, Naoki Takakura, Kentaro Kasa, Teppei Komatsu, Dai Kejia, Misato Yoshioka, Hirotaka James Okano, Hiroaki Onoe   +8 more
wiley   +1 more source

Comprehensive evidence for the pathogenicity of the <i>BRCA2</i> c.7847C>T (p.Ser2616Phe) variant specific to the Japanese population. [PDF]

J Med Genet
Yamazawa K, Ueki A, Kuga A, Hinoi T, Niitsu H, Minatogawa M, Kawano J, Minami S, Okawa M, Takei J, Ichikawa M, Enokido K, Akimaru N, Torii M, Tsuyuki S, Iguchi C, Inoue T, Nakajima T, Watanabe N, Tanoshima M, Harada-Shoji N, Taruno K, Arai M, Murakami F, Ogawa M, Tamura K, Sugano K, Tanakaya K, Inoue S, Murakami H, Nakashima M, Makabe T, Kosaki K, Matsui A.   +33 more
europepmc   +1 more source

A Modular Liver–Microbial Microfluidic Platform to Evaluate Therapeutic and Adverse Effects of Microbial Metabolites

Advanced Healthcare Materials, EarlyView.
This study introduces a modular microfluidic platform that connects liver cells with live microbes to mimic key aspects of the gut–liver interaction in steatosis. Using this system, both microbial metabolites and live bacteria significantly reduced fat accumulation in liver cells, but live microbes triggered inflammation and broader metabolic changes ...
Hsih‐Yin Tan, In Young Hwang, Nanthini Jayabalan, Hui Ling Lee, Louis Jun Ye Ong, Chwee Teck Lim, Matthew Wook Chang, Yi‐Chin Toh   +7 more
wiley   +1 more source

WormSpot: a machine learning-powered viability scoring platform in <i>C. elegans</i> for <i>Candida</i> pathogenicity studies. [PDF]

Microbiol Spectr
Lee JGW, Ong VEY, Zhang D.
europepmc   +1 more source

A Novel Perfused Full‐Thickness Human Skin Microphysiological System for Modeling Injury, Regeneration, Tumor Pathophysiology, and Therapeutics Development

Advanced Healthcare Materials, EarlyView.
What if human skin could remain fully alive and functional outside the body for weeks? A New Alternative Method (NAM) based on a vascularized full‐thickness skin microphysiological system achieves precisely this, preserving native vasculature, resident immunity, and metabolic activity for up to three weeks, while faithfully recapitulating radiation ...
Yusuf Surucu, Hamid Malekzadeh, Alexa Rivera Del Rio Hernandez, Naresh Mahajan, Ethan Banks, Dayyan Ur Rahman, José A. Arellano, Katherine S. Yang, Alexey Altman, G.V. Naveen Kumar, Matthew L. Steinhauser, Jeffrey A. Gusenoff, J. Peter Rubin, Asim Ejaz   +13 more
wiley   +1 more source