Results 291 to 300 of about 1,083,203 (341)

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

Corrigendum to "Compendium of Clinical Variant Classification for 2,246 Unique <i>ABCA4</i> Variants to Clarify Variant Pathogenicity in Stargardt Disease Using a Modified ACMG/AMP Framework". [PDF]

Hum Mutat
europepmc   +1 more source

Fatty acids in filamentous pathogenic fungi: Multidimensional regulation and pathogenic mechanisms. [PDF]

Virulence
Lin H, Peng Y.
europepmc   +1 more source

Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity

Cell, 2015
Jellert T. Gaublomme, N. Yosef, Youjin Lee, Rona S. Gertner, Li V. Yang, Chuan Wu, P. Pandolfi, T. Mak, R. Satija, A. Shalek, V. Kuchroo, Hongkun Park, A. Regev   +12 more
semanticscholar   +1 more source

Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis

Advanced Healthcare Materials, EarlyView.
This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han, Weiping Lin, Yuanxiong Cao, Patricia Murray, Bettina Wilm, Stephen J McWilliam, Jude Curran, Ruoxiao Xie   +7 more
wiley   +1 more source

Pathogenic Variability of <i>Colletotrichum</i> Isolates From the Southern Areas of Coffee (<i>Coffea arabica</i> L.) Producing in Ethiopia. [PDF]

Int J Food Sci
Negasso AW.
europepmc   +1 more source

Novel Drug‐Testing Platform for Vascular Injury‐induced Intimal Hyperplasia Using a Microphysiological System

Advanced Healthcare Materials, EarlyView.
This study develops a 3D vascular injury model using a microphysiological system that mimics key features of intimal hyperplasia. Antiproliferative drugs reduced VSMC proliferation but worsened endothelialdenudation. A combination of diphenyleneiodonium and quercetin effectively reduced proliferation and migration of VSMC and inflammation while ...
Ungsig Nam, HyeMi Kim, Jeong Ah Kim, Ki‐Hwan Nam, Kye‐Sung Lee, Hwan Hur, Jessie S. Jeon, Ji Yong Bae   +7 more
wiley   +1 more source

T-DNA Mutagenesis Reveals FpPer1 as a Dual-Function Regulator of Virulence and Fungicide Resistance in <i>Fusarium pseudograminearum</i>. [PDF]

J Fungi (Basel)
Li H, Zhang P, Song X, Li H, Chen C, Wang L, Wang Z, Hao L, Li Y, Wang X, Kang J, Li H, Wang M, Ding S.   +13 more
europepmc   +1 more source

Biologically Active Implants Prevent Mortality in a Mouse Sepsis Model

Advanced Healthcare Materials, EarlyView.
A modular, triple‐action titanium implant is developed to prevent implant‐associated infections by repelling bacteria, killing pathogens, and enhancing tissue integration. Coatings with phage cocktails targeting P. aeruginosa and S. aureus show significant bacterial reduction and improved survival in a mouse sepsis model.
Martin Stark, Fereshteh Bayat, Sara Rahmani, Mathura Thirugnanasampanthar, Taylor Kramer, Elise Schwarz, David Wilson, Jeffrey I. Weitz, Zeinab Hosseinidoust, Tohid F. Didar   +9 more
wiley   +1 more source

Pathogenicity and contact transmissibility of clade IIb MPXV in African dormice. [PDF]

Emerg Microbes Infect
Wang X, Liu L, He M, Shi S, Nie X, Sun Y, Ren W, Wang Y, Zhang Y, Han H, Wang Z, Liu Z, Shang C, Jiang Q, Guo Z, Wang J, Ou C, Li X, Zhao Z.   +18 more
europepmc   +1 more source