Results 131 to 140 of about 931,796 (247)

Retraction: A Human Torque Teno Virus Encodes a MicroRNA That Inhibits Interferon Signaling.

PLoS Pathogens, 2021
PLOS Pathogens Editors
doaj   +1 more source

Correction: Extracellular vesicles from diverse fungal pathogens induce species-specific and endocytosis-dependent immunomodulation. [PDF]

PLoS Pathog
Kwaku GN, Jensen KN, Simaku P, Floyd DJ, Saelens JW, Reardon CM, Ward RA, Basham KJ, Hepworth OW, Vyas TD, Zamith-Miranda D, Nosanchuk JD, Vyas JM, Harding HB.   +13 more
europepmc   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

AMR surveillance in Canada: Insights from the 2025 Priority Pathogen List. [PDF]

PLoS One
Abdesselam K, Muchaal PK, Mishra A, Ngendabanka RJ, Amaratunga K, Mittal S, Rudnick W, Crago AL, Mitchell R, Alexandre S, Lary T.   +10 more
europepmc   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Prevalence of potential enteric pathogens in diarrheic and non-diarrheic foals in Brazil. [PDF]

J Vet Diagn Invest
Basso RM, Cerri FM, Braga PRC, Silva ROS, de Araújo Júnior JP, Oliveira-Filho JP, Pantoja JCF, Ribeiro MG, Arroyo LG, Borges AS.   +9 more
europepmc   +1 more source

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

First report of Providencia rettgeri, Colpodella spp., Ehrlichia spp., and Rickettsia hoogstraalii in ticks infesting goats of Pakistan. [PDF]

PLoS Negl Trop Dis
Ullah S, Sher H, Cossío-Bayúgar R, Giantsis IA, Haleem S, Niaz S, von Fricken ME, Khan A.   +7 more
europepmc   +1 more source

Pathogenicity Underestimated [PDF]

Deutsches Ärzteblatt international, 2015
openaire   +2 more sources

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source