Results 161 to 170 of about 2,694,235 (387)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Retraction: Epstein-Barr Virus Nuclear Antigen 3C Stabilizes Gemin3 to Block p53-mediated Apoptosis.

PLoS Pathogens, 2021
PLOS Pathogens Editors
doaj   +1 more source

RESOURCE AND COMPETITIVE DYNAMICS SHAPE THE BENEFITS OF PUBLIC GOODS COOPERATION IN A PLANT PATHOGEN [PDF]

, 2012
Thomas G. Platt, Clay Fuqua, James D. Bever   +2 more
openalex   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Correction: rational development of an attenuated recombinant cyprinid herpesvirus 3 vaccine using prokaryotic mutagenesis and in vivo bioluminescent imaging. [PDF]

PLoS Pathogens, 2015
PLOS Pathogens Staff
doaj   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

The Top 10 fungal pathogens in molecular plant pathology.

Molecular plant pathology, 2012
R. Dean, J. V. van Kan, Z. Pretorius, K. Hammond-Kosack, A. Di Pietro, P. Spanu, J. Rudd, M. Dickman, R. Kahmann, J. Ellis, G. Foster   +10 more
semanticscholar   +1 more source

Testing of Great Bay Oysters for Two Protozoan Pathogens [PDF]

, 2008
Two protozoan pathogens, Haplosporidium nelsoni (MSX) and Perkinsus marinus (Dermo) are known to be present in Great Bay oysters. With funds provided by the New Hampshire Estuaries Project (NHEP), the Marine Fisheries Division of New Hampshire Fish and ...
Nelson, John I.
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Identification of bacterial and fungal pathogens directly from clinical blood cultures using whole genome sequencing

, 2023
Stephen W. Peterson, Walter Demczuk, Irene Martín, Heather J. Adam, Amrita Bharat, M. R. Mulvey   +5 more
openalex   +1 more source