Results 121 to 130 of about 807,832 (329)
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
Molecular Oncology, EarlyView.TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam +9 more
wiley +1 more source
Journal of Coloproctology, 2012 The presence of cutaneous metastases (CM) from a digestive tract cancer is infrequent, appearing in less than 5% of the cases. Given the low incidence of metastasis from colon adenocarcinoma, an unusual case that occurred in the Colorectal Surgery ...
Caroline Merci Caliari de Neves Gomes +4 more
doaj
NOTES ON THE CHROMOPHILIC MATERIAL IN THE MOTOR CELLS OF BRAIN AND CORD, NORMAL (ANIMAL) AND PATHOLOGICAL (HUMAN), AND ON THE REACTION (ACID OR ALKALINE) OF THE CORTEX AND CEREBROSPINAL FLUID [PDF]
, 1899 John G. Turner
openalex +1 more source
Molecular Oncology, EarlyView.Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé +7 more
wiley +1 more source
MYOCARDIODYSTROPHY IN CHILDREN FROM THE POINT OF VIEW OF PATHOANATOMIST
Вопросы современной педиатрии, 2011 The article discusses questions of etiology, pathogenesis and morphological signs of myocardiodystrophy in different periods of childhood. Functional disorders of cardiogenesis and hypoxic cardiopathy could be main causes of a disease.
B. I. Glukhovets
doaj +2 more sources
Body and will, being an essay concerning will in its metaphysical, physiological, and pathological aspects. [PDF]
, 1884 Henry Maudsley
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Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
Molecular Oncology, EarlyView.CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak +14 more
wiley +1 more source