Quadrant asymmetry alteration of deep retinal capillary plexus degeneration in pathological myopia [PDF]
Journal of Translational MedicineBackground To measure quadrant asymmetry (QA) alterations of macular retinal microvascular density and determine their effect on pathological myopia. Methods Optical coherence tomography angiography (OCTA) images of 20 control, 42 simple high myopia and ...
Yilei Shao, Meixiao Shen, Fan Lu, Jie Ye
doaj +3 more sources
Metabolomic Profiling of Aqueous Humor from Pathological Myopia Patients with Choroidal Neovascularization. [PDF]
Metabolites, 2023 Choroidal neovascularization (CNV) is a severe complication observed in individuals with pathological myopia (PM). Our hypothesis is that specific metabolic alterations occur during the development of CNV in patients with PM.
Wei Q +6 more
europepmc +4 more sources
Automatic detection of pathological myopia using machine learning [PDF]
Scientific Reports, 2021 Pathological myopia is a severe case of myopia, i.e., nearsightedness. Pathological myopia is also known as degenerative myopia because it ultimately leads to blindness.
Namra Rauf, Syed Omer Gilani, Asim Waris
doaj +3 more sources
Reduced Radial Peripapillary Capillary in Pathological Myopia Is Correlated With Visual Acuity [PDF]
Frontiers in Neuroscience, 2022 PurposeTo quantify the radial peripapillary capillary (RPC) density and the peripapillary retinal nerve fiber layer (pRNFL) thickness in pathological myopia and examine associations among these factors and best-corrected visual acuity (BCVA).MethodsThe ...
Jie Ye +6 more
doaj +3 more sources
Identifying pathological myopia associated genes with GenePlexus in protein-protein interaction network [PDF]
Frontiers in GeneticsIntroductionPathological myopia, a severe form of myopia, is characterized by an extreme elongation of the eyeball, leading to various vision-threatening complications.
Yuanyuan Luo +5 more
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PMPred-AE: a computational model for the detection and interpretation of pathological myopia based on artificial intelligence [PDF]
Frontiers in MedicineIntroductionPathological myopia (PM) is a serious visual impairment that may lead to irreversible visual damage or even blindness. Timely diagnosis and effective management of PM are of great significance.
Hong-Qi Zhang +8 more
doaj +3 more sources
The causal impact of gut microbiota and metabolites on myopia and pathological myopia: a mediation Mendelian randomization study [PDF]
Scientific ReportsMyopia, a major cause of irreversible visual impairment globally, is projected to affect about 25% of the world’s population by 2025. Myopia progresses through childhood and adolescence, necessitating frequent prescription updates.
Jingwen Hui +4 more
doaj +3 more sources
Pathological myopia-induced antioxidative proteins in the vitreous humor. [PDF]
Ann Transl Med, 2020 Background This study aimed to investigate differentially expressed proteins in the vitreous humor (VH) of pathological myopia (PM) and normal eyes. Methods VH samples were collected from patients undergoing surgical treatment for rhegmatogenous retinal ...
Wei Q +6 more
europepmc +4 more sources
MedComm – Future Medicine, 2023 This study aimed to investigate the awareness of high and pathological myopia among patients with high myopia. A cross‐sectional multicenter survey involving both physicians and patients was conducted between February and April 2021.
Jing Zhao +11 more
doaj +2 more sources
Vascular Changes of the Choroid and Their Correlations With Visual Acuity in Pathological Myopia. [PDF]
Invest Ophthalmol Vis Sci, 2022 Purpose Photoreceptor loss plays a role in visual impairment in pathological myopia. As the nutrition and oxygen demands of photoreceptors are mainly supported by the choroidal vessels, we aimed to investigate changes in the choroidal vasculature and ...
Wang Y +12 more
europepmc +2 more sources