Results 61 to 70 of about 1,076,017 (253)

Myopia and associated pathological complications [PDF]

Ophthalmic and Physiological Optics, 2005
AbstractBesides the direct economic and social burden of myopia, associated ocular complications may lead to substantial visual loss. In several population and clinic‐based cohorts, case–control and cross‐sectional studies, higher risks of posterior subcapsular cataract, cortical and nuclear cataract in myopic patients were reported. Patients with high
Seang-Mei, Saw, Gus, Gazzard, Edwin Chan, Shih-Yen, Wei-Han, Chua   +3 more
openaire   +2 more sources

TGF-β2 levels in the aqueous humor are elevated in the second eye of high myopia within two weeks after sequential cataract surgery

Scientific Reports, 2022
Transforming growth factor-β (TGF-β) is the critical regulator of physiological and pathological conditions in lens. The TGF-β signaling pathway is closely associated with high myopia patients.
Weijia Yan, Yaping Zhang, Junguo Cao, Hong Yan   +3 more
doaj   +1 more source

Peripapillary Detachment in Pathologic Myopia [PDF]

Archives of Ophthalmology, 2003
To describe peripapillary detachment in pathologic myopia (PDPM), a newly recognized fundus lesion.Retrospective medical record review.We evaluated a series of myopic eyes that had a yellow-orange elevation of the retina and retinal pigment epithelium at the inferior border of the myopic conus.Twenty eyes of 15 patients were identified during a 17-year
K Bailey, Freund, Antonio P, Ciardella, Lawrence A, Yannuzzi, Alfredo, Pece, Mauro, Goldbaum, Gregg T, Kokame, Dennis, Orlock   +6 more
openaire   +2 more sources

Evaluation of the Efficacy and Safety of Satralizumab in a Pregnant NMOSD Patient With AQP4/MOG‐IgG Dual Seropositive: A Case Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Neuromyelitis Optica Spectrum Disorder (NMOSD) is a chronic autoimmune neuroinflammatory disease, typically characterized by antibodies against aquaporin 4 (AQP4‐IgG) or myelin oligodendrocyte glycoprotein (MOG‐IgG). Simultaneous seropositivity for both antibodies in a single patient is exceedingly rare.
Yeting Luo, Shuhua Xie, Xianghong Liu
wiley   +1 more source

Imaging of Pathologic Myopia

Asia-Pacific Journal of Ophthalmology, 2019
Pathologic myopia (PM) is a major cause of irreversible visual impairment worldwide and especially in East Asian countries. The complications of PM include myopic maculopathy, myopic macular retinoschisis, dome-shaped macula, and myopic optic neuropathy.
Kyoko, Ohno-Matsui, Yuxin, Fang, Kosei, Shinohara, Hiroyuki, Takahashi, Kengo, Uramoto, Tae, Yokoi   +5 more
openaire   +2 more sources

Characterization of Microplastics in Human Gastric Cancer and Control Tissues and Analysis of Associated Genetic Features

Advanced Healthcare Materials, EarlyView.
This study characterizes the presence of microplastics in human normal gastric, para‐tumor, and gastric tumor tissue and confirms the association between microplastic exposure and lymph node metastasis in gastric cancer. This study explores the transcriptomic changes induced by microplastic exposure, laying the foundation for further investigation into
Liqiao Chen, Jialin Li, Yan Wu, Han Bao, Xuesong Yang, Guoqing Lv, Ke Ji, Ji Zhang, Xiaojiang Wu, Kai Zhou, Jieli Xu, Jiatian Tang, Xiyuan Han, Anqiang Wang   +13 more
wiley   +1 more source

Phacoemulsification with Negative Power IOL Implantation in Pathological Myopia: A Life-changing Procedure

Delhi Journal of Ophthalmology
Pathological myopia refers to a spherical equivalent of −8.00 D or more or axial length of 32.5 mm or more. Pathological myopia can lead to complications of the posterior segment such as retinal detachment and staphyloma in long term.
Dharti Punjabi, Devika S. Joshi, Vishranti Khandelwal   +2 more
doaj   +1 more source

Genetic and Phenotypic Features of the Five Known Polyaminopathies: A Critical Narrative Review

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Polyaminopathies are a recently described family of rare genetic neurodevelopmental disorders. Polyaminopathies disrupt the biosynthesis of the primary polyamines: putrescine, spermidine, and spermine. Snyder–Robinson syndrome results from hemizygous loss‐of‐function variants in the spermine synthase (SMS) gene, resulting in decreased or ...
Elizabeth A. VanSickle, Sara M. Sarasua, Tracy Lowe, Christopher L. Farrell, Luigi Boccuto, Charles Schwartz, Anthony E. Pegg, Angela Peron, Victor Faundes, Mythily Ganapathi, Wendy K. Chung, Alban Ziegler, Floris Hofstede, Clément Prouteau, Katharina Steindl, Colleen Olson, Orrin Devinsky, Teresa L. Mastracci, Robert A. Casero Jr., Tracy Murray Stewart, Susan Gilmour, Teri Koerner, Mary Jo Kutler, Surender Rajasekaran, Julianne Michael, André S. Bachmann, Caleb P. Bupp   +26 more
wiley   +1 more source

Chinese Parents’ Perspective on Myopia: A Cross-Sectional Survey Study

Ophthalmology and Therapy, 2023
Introduction The prevalence of myopia in young generations has dramatically increased over the years, especially in China. This study aims to understand Chinese parents’ perspectives on myopia for further improvement of treatment compliance and informing
Yangyi Huang, Zhi Chen, Bingjie Wang, Jing Zhao, Xueyi Zhou, Xiaomei Qu, Xiaoying Wang, Xingtao Zhou   +7 more
doaj   +1 more source

The complexity of dementia development and its comorbidities: The collaborative cross‐mouse population for multivarious tasks approach

Animal Models and Experimental Medicine, EarlyView.
The increasing prevalence of dementia and related neurodegenerative diseases—including Alzheimer's disease, Parkinson's disease, multiple sclerosis, and amyotrophic lateral sclerosis—poses a growing public health challenge. These conditions have traditionally been studied as isolated central nervous system disorders, but emerging evidence points to ...
Osayd Zohud, Iqbal M. Lone, Kareem Midlej, Fuad A. Iraqi   +3 more
wiley   +1 more source