Results 51 to 60 of about 7,324,524 (245)

Overexpression of miR-221 in sudden death with cardiac hypertrophy patients

Heliyon, 2018
Background: Cardiac hypertrophy is a well-known risk factor for heart failure and sudden cardiac death (SCD). On the other hand, physiological cardiac hypertrophy is often observed in young healthy men, and it is difficult to predict SCD in cardiac ...
Yu Kakimoto, Masayuki Tanaka, Hideki Hayashi, Keiko Yokoyama, Motoki Osawa   +4 more
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Towards a national strategy for digital pathology in Switzerland. [PDF]

, 2022
Precision medicine is entering a new era of digital diagnostics; the availability of integrated digital pathology (DP) and structured clinical datasets has the potential to become a key catalyst for biomedical research, education and business development.
Michielin, O, Moch, H, Koelzer, VH, Rottenberg, Sven, Perren, A, Koelzer, Viktor Hendrik, Rubin, Mark A., de Leval, Laurence, Michielin, Olivier, Rubin, MA, Grobholz, R., Grobholz, Rainer, Grobholz, R, Koelzer, V.H., Kipar, A, Janowczyk, A, Tolnay, M, Baumhoer, D., Rubbia-Brandt, L, Dirnhofer, S., Zlobec, I., Zlobec, I, Sempoux, C., Rubin, Mark A, Merkler, Doron, Koelzer, Viktor Hendrik; https://orcid.org/, Janowczyk, A., Janowczyk, Andrew, Kipar, Anja, Tolnay, M., Rottenberg, S., Michielin, O., Perren, A., Moch, H., Rubin, M.A., Dirnhofer, Stefan, Merkler, D., Moch, Holger, Perren, Aurel, de Leval, L, Baumhoer, Daniel, Baumhoer, D, Zlobec, Inti, Kipar, A., Rubbia-Brandt, L., Sempoux, Christine, Sempoux, C, Rubbia-Brandt, Laura, Dirnhofer, S, Merkler, D, Tolnay, Markus, Rottenberg, S, Swiss Digital Pathology Consortium (SDiPath), de Leval, L.   +53 more
core   +2 more sources

Clinicopathological features of 71 patients with amyloidosis nephropathy

Linchuang shenzangbing zazhi, 2021
Objective To explore the clinicopathological features of patients with amyloidosis nephropathy to provide more rationales for clinical diagnosis and treatment.Methods From December 1997 to December 2019,clinicopathological data were retrospectively ...
Zhao Xue, Yu Che, Wang Rong
doaj  

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

European Society of Pathology Task Force on Quality Assurance in Molecular Pathology; Royal College of Pathologists. Guidance for laboratories performing molecular pathology for cancer patients.

, 2014
Molecular testing is becoming an important part of the diagnosis of any patient with cancer. The challenge to laboratories is to meet this need, using reliable methods and processes to ensure that patients receive a timely and accurate report on which ...
Groenen, P, Normanno, N, Timens, W, Murray, S, Solé, F, Cree, Ia, Schuuring, E, Royal, College of Pathologists, STANTA, GIORGIO, Thunnissen, E, Edsjö, A, Deans, Z, Rouleau, E, Dietel, M, Van Krieken, Jh, European, Society of Pathology Task Force on Quality Assurance in Molecular Pathology, Ligtenberg, Mj, Dequeker, E   +17 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Teaching veterinary clinical pathology to undergraduate students: an integrated European project RID F-5412-2011

, 2007
Background: Veterinary clinical pathology is a relatively new and emerging discipline in Europe that has gained momentum with the recent establishment of a specialty college.
Knottenbelt CM, Braun JP, Godeau JM, Moritz A, Gaal T, Ceron JJ, Sankari SM, Larkin HA, LUBAS, GEORGE, Papasouliotis K   +9 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source