Results 71 to 80 of about 1,561,373 (232)

Squamous cell carcinoma in situ crocodilus: Plaques of squamous cell carcinoma in situ simulating crocodile skin

open access: yesJAAD Case Reports, 2022
Nancy H. Kim, MD   +4 more
doaj   +1 more source

SPRAYDYE: a phase I/II randomised pilot study to assess the safety and feasibility of topically applied AKRO-6qcICG, a cathepsin-activatable fluorescent imaging agent, for real-time intraoperative resection margin assessment in breast-conserving surgery

open access: yesFrontiers in Surgery
IntroductionThe incidence of tumour-positive surgical resection margins (TPRMs) after breast-conserving surgery (BCS) remains high, ranging from 10 to 40%.
Cedric M. W. Pesch   +23 more
doaj   +1 more source

Early‐Phase Research in Pediatric Neuro‐Oncology

open access: yes
Pediatric Blood &Cancer, EarlyView.
Jonathan Cunningham
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

PARÂMETROS BIOQUÍMICOS DE AVALIAÇÃO DA FUNÇÃO RENAL E HEPÁTICA DE EQUINOS COM CÓLICA SUBMETIDOS A LAPAROTOMIA, SOBREVIVENTES OU NÃO

open access: yesCiência Animal Brasileira, 2012
We examined 46 adult horses - six healthy, as control, (group 1) and 40 horses with colic submitted to treatment by laparotomy. Twenty animals had no postoperative complication (group 2), and twenty died or were euthanized from seven to ten days after ...
Paula Alessandra Di Filippo   +3 more
doaj  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Retrospective of Clinical Pathology of Herd Pigs in Extensive and Intensive Breeding

open access: yesScientific Papers Animal Science and Biotechnologies
The main characteristic of the herd of pigs in extensive and intensive breeding is the presence of breeding diseases of different aetiology. The research aimed to monitor the frequency of breeding diseases and organize the implementation of prophylactic ...
Jovan Bojkovski   +10 more
doaj  

An Analysis of the Correlation Between Clinical Indexes and Pathological Classifications in 202 Patients with Lupus Nephritis

open access: yesJournal of Inflammation Research, 2021
Bang-Pin Pan,1,* Zhi-Jian Feng,2,* Xiao-Lan Li,1 Li-Ping He,3 Dong Jiang,1 Rui-Xian Zhang,1 Wen-Ting Cao,1 Mei Cai,1 Yun-Feng Bi,1 Wen-Fang Wang,1 Chun-Yan Luan1 1Department of Dermatology, The Second Affiliated Hospital of Kunming Medical ...
Pan BP   +10 more
doaj  

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