Results 61 to 70 of about 1,686,445 (282)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The Pathology Workforce and Clinical Licensure

Academic Pathology, 2018
There has been a recent recognition of the need to prepare PhD-trained scientists for increasingly diverse careers in academia, industry, and health care.
Robin G. Lorenz MD, PhD, Donald S. Karcher MD, Michael D. Gautreaux PhD, Melvin Limson PhD, Dani S. Zander MD   +4 more
doaj   +1 more source

Pathology informatics fellowship training: Focus on molecular pathology

Journal of Pathology Informatics, 2014
Background: Pathology informatics is both emerging as a distinct subspecialty and simultaneously becoming deeply integrated within the breadth of pathology practice. As specialists, pathology informaticians need a broad skill set, including aptitude with
Diana Mandelker, Roy E Lee, Mia Y Platt, Gregory Riedlinger, Andrew Quinn, Luigi K. F. Rao, Veronica E Klepeis, Michael Mahowald, William J Lane, Bruce A Beckwith, Jason M Baron, David S McClintock, Frank C Kuo, Matthew S Lebo, John R Gilbertson   +14 more
doaj   +1 more source

Translational milestones in urologic pathology: integrating molecular diagnostics across cancer types

In its first decade, The Journal of Pathology: Clinical Research has become a leading source of translational studies advancing molecular diagnostics in cancer, particularly in urologic pathology.
Acosta, Andres M., Matoso, Andres
core   +1 more source

Gastrointestinal pathology : recent developments and concepts

, 2014
Editorial: This issue of the Journal of Clinical Pathology comprises a series of review articles on some of the latest developments in gastrointestinal ...
Montgomery, Elizabeth A., Chetty, Runjan, Lee, C. S., Lee, Cheok Soon (R13259), Montgomery, E. A., Chetty, R.   +5 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Anatomic and clinical pathology : proceedings of the VIII World congress of anatomic and clinical pathology /

, 1973
Sponsored by the World Association of Anatomic and Clinical Pathology Societies.Met lit ...
World Association of Anatomic and Clinical Pathology Societies., World congress of Anatomic and Clinical Pathology(8 :1972 :Munich), Nordmann, Martin,1895-1980(viaf)25000176edt, Excerpta Medica Foundation.   +3 more
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Clinical analysis of 94 cases of ocular adnexal lymphomas

Precision Medical Sciences
To investigate the imaging manifestations and pathological features of ocular adnexal lymphoma (OALs) in order to provide relevant information for ophthalmologists.
Yu‐ying Sun, Shu‐ai Luo, Chun‐yu Huang   +2 more
doaj   +1 more source