Results 111 to 120 of about 3,893,490 (356)

The effects of L-Cysteine on Alzheimer’s disease pathology in APOE2, APOE3, and APOE4 homozygous mice [PDF]

open access: diamond, 2020
Stephen G Cieslak   +9 more
openalex   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Anatomical and Histological Analyses of Rare Pancake Kidney

open access: yesAnatomia
During anatomical dissection of a female body donor at the Howard University College of Medicine, a rare renal anomaly was discovered. Detailed anatomical and histological analyses on this anomaly were compared to a normal kidney from another donor and ...
Lindsey Koper   +5 more
doaj   +1 more source

An Autopsy Confirmed Case of Amyotrophic Lateral Sclerosis with TDP Pathology [PDF]

open access: diamond, 2022
Yu-Ri Je   +17 more
openalex   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Artificial Intelligence in Breast Cancer Diagnosis and Treatment: Advances in Imaging, Pathology, and Personalized Care

open access: yesLife
Breast cancer is the most prevalent cancer worldwide, affecting both low- and middle-income countries, with a growing number of cases. In 2024, about 310,720 women in the U.S. are projected to receive an invasive breast cancer diagnosis, alongside 56,500
Petar Uchikov   +12 more
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Clinical predictive significance of biomarker molecules elevation during the transition period in in cattle suffering from different pathological states: A review

open access: yesOpen Veterinary Journal
The transition period (TP), which extends from 3 weeks prior to 3 weeks post parturition, is a critical period regarding the health, productivity, and profitability of dairy animals, during which most health disorders arise, include lameness, mastitis ...
Mohamed Tharwat   +2 more
doaj   +1 more source

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