Results 131 to 140 of about 2,661,536 (309)

PATHOLOGY [PDF]

open access: yesBritish Journal of Ophthalmology, 1946
openaire   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Reticuloendothelial: Amyloidosis

open access: yes, 1900
Amyloidosis: liver, spleen, kidney. Note: This specimen was seen in General Pathology.
MUSC Department of Pathology and Laboratory Medicine
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

The future of speech pathology in aged care: Students’ confidence and interest in working with older people

open access: yes, 2015
Australia’s demographic future and need for allied health staff equipped to provide services to growing numbers of older people with complex care needs have been documented.
Hewetson, Ronelle   +4 more
core  

Large Congenital Epulis in a Newborn: Diagnosis and Management

open access: yesEar, Nose & Throat Journal, 2020
Neha Jain MBBS, MS(ENT)   +2 more
doaj   +1 more source

Pathology of Rural Guidance Projects on Collection and Disposal of Surface Water

open access: yesتحقيقات جغرافيايی, 2017
One of the strategies developed in the first decade after the Islamic Revolution of Iran with the aim of achieving development in rural areas, is the rural guidance of surface water plan.
Moses Kamanroodi Kojouri, Afsaneh Majidi
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

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