Results 151 to 160 of about 3,537,472 (355)

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

open access: yesMolecular Oncology, Volume 19, Issue 5, Page 1508-1516, May 2025.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang   +3 more
wiley   +1 more source

Diagnóstico investigativo de patologias no trato genital de búfalas criadas extensivamente, no estado do Amapá, Amazônia, Brasil

open access: yesBrazilian Journal of Veterinary Medicine, 2016
RESUMO. Ribeiro H.F.L., Mourão F.R.P., Monteiro F.J.C., Rolim Filho S.T. & Vale W.G. Diagnosis of investigative pathology in the genital tract of buffaloes raised extensively in the state of Amapá, Amazon, Brazil. [Diagnóstico investigativo de patologias
Haroldo Francisco Lobato Ribeiro   +4 more
doaj  

Multi‐omics profiling reveals key factors involved in Ewing sarcoma metastasis

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1002-1028, April 2025.
Using a mouse model that recapitulates the spread of tumor cells within the body, we have profiled paired tumors and metastasis samples using a multiomics approach combining different layers of biological information. We identified key genes that drive metastasis in Ewing sarcoma.
Mariona Chicón‐Bosch   +11 more
wiley   +1 more source

Pathology in Practice [PDF]

open access: yes, 2017
Lofts, R   +3 more
core   +1 more source

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

open access: yesMolecular Oncology, Volume 19, Issue 5, Page 1371-1385, May 2025.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa   +13 more
wiley   +1 more source

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

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