Results 191 to 200 of about 2,892,074 (310)
Data-driven modelling of tau pathology reveals distinct progressive supranuclear palsy subtypes. [PDF]
Cullinane PW +26 more
europepmc +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
RETRACTION: Numb Promotes Autophagy through p53 Pathway in Acute Kidney Injury Induced by Cisplatin
Analytical Cellular Pathology
doaj +1 more source
Insights into artificial intelligence-based digital pathology in hepatobiliary and pancreatic cancer. [PDF]
Huang HY, Kow AWC, Fan ZQ, Lv GY.
europepmc +1 more source
Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Alzheimer's Disease Beyond Amyloid: Lessons From Atherosclerosis. [PDF]
Ciaccio M, Agnello L.
europepmc +1 more source
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source

