Results 51 to 60 of about 3,537,472 (355)

Associations of Social Vulnerability Index With Pathologic Myocardial Findings at Autopsy

open access: yesFrontiers in Cardiovascular Medicine, 2021
Background: Social vulnerability is an important determinant of cardiovascular health. Prior investigations have shown strong associations of social determinants of health with cardiovascular risk factors, imaging findings, and clinical events.
Ashwin Sunderraj   +21 more
doaj   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Expert consensus on precision detection of intrahepatic cholangiocarcinoma (2024 edition)

open access: yesZhongguo Linchuang Yixue
Intrahepatic cholangiocarcinoma (ICC) is a highly heterogeneous tumor, and molecular profiling serves as the foundation for personalized treatment of ICC.
Pathology Group, Chinese Society of Liver Cancer of Chinese Anti-Cancer Association; Liver Pathology Group, Chinese Society of Pathology of Chinese Anti-Cancer Association; Tumor Pathology Committee of Shanghai Anti-Cancer Association, Shanghai 200032, China
doaj   +1 more source

An updated review on bluetongue virus: epidemiology, pathobiology, and advances in diagnosis and control with special reference to India

open access: yesVeterinary Quarterly, 2020
Bluetongue (BT) is an economically important, non-contagious viral disease of domestic and wild ruminants. BT is caused by BT virus (BTV) and it belongs to the genus Orbivirus and family Reoviridae.
Mani Saminathan   +11 more
doaj   +1 more source

Multi-Modality Pathology Segmentation Framework: Application to Cardiac Magnetic Resonance Images [PDF]

open access: yesarXiv, 2020
Multi-sequence of cardiac magnetic resonance (CMR) images can provide complementary information for myocardial pathology (scar and edema). However, it is still challenging to fuse these underlying information for pathology segmentation effectively. This work presents an automatic cascade pathology segmentation framework based on multi-modality CMR ...
arxiv  

PathAsst: A Generative Foundation AI Assistant Towards Artificial General Intelligence of Pathology [PDF]

open access: yesarXiv, 2023
As advances in large language models (LLMs) and multimodal techniques continue to mature, the development of general-purpose multimodal large language models (MLLMs) has surged, offering significant applications in interpreting natural images. However, the field of pathology has largely remained untapped, particularly in gathering high-quality data and
arxiv  

Ligand recognition by 14‐3‐3 proteins requires negative charges but not necessarily phosphorylation

open access: yesFEBS Letters, Volume 599, Issue 6, Page 838-847, March 2025.
Interactions of 14‐3‐3 proteins with their binding partners are attributed to phosphorylation of the binding partners. In this work, we show that at least one negative charge is required for the peptides to bind 14‐3‐3ε, although phosphorylation is not necessary, and that two negative charges are preferable for high affinity binding.
Seraphine Kamayirese   +2 more
wiley   +1 more source

Underactive bladder - an underestimated entity [PDF]

open access: yes, 2020
Introduction. The concept of underactive bladder is relatively new. Currently there is no generally accepted definition of this pathology. Diagnosis depends on urodynamic findings, and symptoms are usually rare and intricated with the symptoms of other ...
Bratu, Ovidiu Gabriel   +8 more
core   +1 more source

SAM-Path: A Segment Anything Model for Semantic Segmentation in Digital Pathology [PDF]

open access: yesarXiv, 2023
Semantic segmentations of pathological entities have crucial clinical value in computational pathology workflows. Foundation models, such as the Segment Anything Model (SAM), have been recently proposed for universal use in segmentation tasks. SAM shows remarkable promise in instance segmentation on natural images.
arxiv  

Human colon organoid differentiation from induced pluripotent stem cells using an improved method

open access: yesFEBS Letters, Volume 599, Issue 6, Page 912-924, March 2025.
We compared established protocols to differentiate induced pluripotent stem cells into colon organoids and found that activation of bone morphogenetic protein 2 signaling induced gene expression of colon‐specific markers. Adenovirus‐mediated transduction of the transcription factors HOXD13 or SATB2 further enhanced colonic gene expression, suggesting ...
I‐Ting Lee   +4 more
wiley   +1 more source

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