Results 81 to 90 of about 4,237,903 (401)

Diminished Prolinemia in Chronic Chagasic Patients: A New Clue for Disease Pathology?

open access: yesMolecules, 2019
Trypanosoma cruzi, the etiological agent of Chagas disease, is dependent on proline for a variety of processes, such as energy metabolism, host cell invasion, differentiation, and resistance to osmotic, metabolic, and oxidative stress.
Sandra Carla Rocha   +4 more
doaj   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Characterization of Schu S4 aro mutants as live attenuated tularemia vaccine candidates

open access: yesVirulence, 2020
There is a need for development of an effective vaccine against Francisella tularensis, as this potential bioweapon has a high mortality rate and low infectious dose when delivered via the aerosol route.
Aimee L. Cunningham   +7 more
doaj   +1 more source

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren   +16 more
wiley   +1 more source

Virulent infection of outbred Hartley guinea pigs with recombinant Pichinde virus as a surrogate small animal model for human Lassa fever

open access: yesVirulence, 2020
Arenaviruses, such as Lassa virus (LASV), can cause severe and fatal hemorrhagic fevers (e.g., Lassa fever, LF) in humans with no vaccines or therapeutics.
Shuiyun Lan   +5 more
doaj   +1 more source

How Are We Facing It? Dispatches From Pathology Residents in a COVID-19 Lombardy Hospital

open access: yesFrontiers in Public Health, 2020
At the end of February, the Italian National Health Service reported a hot spot of Coronavirus disease in the Lombardy region. COVID-19 is a highly pathogenic viral infection which poses some challenges for healthcare workers.
Miriam Cieri   +7 more
doaj   +1 more source

Psychohygienic Aspects Of Training Of Disabled Adolescents With Pathology Of The Vision [PDF]

open access: yes, 2017
The objective of this article is to undertake a literature review to familiarize ourselves with the knowledge base; to summarize information about some psycho-hygienic aspects of teaching and visually impaired adolescents, including features of ...
Sasina, O. (Olga)
core   +2 more sources

Pathology of Neurodegenerative Diseases.

open access: yesCold Spring Harbor Perspectives in Biology, 2017
Neurodegenerative disorders are characterized by progressive loss of selectively vulnerable populations of neurons, which contrasts with select static neuronal loss because of metabolic or toxic disorders.
B. Dugger, D. Dickson
semanticscholar   +1 more source

Recent Progress in Pathology and Pathological Anatomy [PDF]

open access: yesThe Boston Medical and Surgical Journal, 1876
n ...
openaire   +3 more sources

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy