Results 91 to 100 of about 23,088 (252)

Renaissance of farnesyltransferase inhibitors in cancer

Journal of Translational Medicine
Background Prenylation (geranylgeranylation or farnesylation) plays an important role in the regulation of RAS proteins. This observation led to development of farnesyltransferase inhibitors (FTI) which were extensively tested in clinical studies of ...
József Tímár, Balázs Hegedűs, Marcell Baranyi   +2 more
doaj   +1 more source

Cold storage effects on immature calliphoridae: Survival limits and forensic consequences for PMI estimation

Journal of Forensic Sciences, EarlyView.
Abstract This study investigated the effects of continuous refrigeration (4°C ± 2°C and 50% ± 5% RH) on the development and survival of immature stages (eggs, first, second, and third instar larvae, and pupae) of four forensically important blowfly species (Chrysomya megacephala, Chrysomya putoria, Hemilucilia segmentaria, and Lucilia cuprina) compared
Larissa Thans Carneiro, Janyra Oliveira‐Costa, Márcia Souto Couri   +2 more
wiley   +1 more source

Biventricular arrhythmogenic cardiomyopathy and sudden cardiac death: forensic perspectives based on autopsy case report

Egyptian Journal of Forensic Sciences
Background Sudden cardiac death (SCD) is a leading global cause of mortality. Among its etiologies is arrhythmogenic cardiomyopathy (ACM), a relatively under-recognized and diagnostically challenging myocardial disorder characterized by fibrofatty ...
Nora Fnon, Hazem Ali, Athar M Khalifa, Enas M A Mostafa, Khadiga M Abdelrahman, Mahrous A Ibrahim   +5 more
doaj   +1 more source

Investigation of eosin Y as a colorimetric sensor for the detection of fentanyl hydrochloride and fentanyl freebase

Journal of Forensic Sciences, EarlyView.
Abstract The increasing prevalence of fentanyl within the illegal global drug market underscores the need for rapid, low‐cost, and straightforward detection methods. Eosin Y demonstrates a measurable color change in the presence of fentanyl, making it a promising candidate for colorimetric sensing and preliminary identification of fentanyl ...
Alan J. Zhou, Melissa M. Dixon, Brady S. Gentle, Genevieve H. Dennison, Kellie L. Tuck   +4 more
wiley   +1 more source

Occupational mortality in older workers: A forensic autopsy‐based evaluation

Journal of Forensic Sciences, EarlyView.
Abstract The aging of the global workforce has led to an increasing number of individuals remaining occupationally active at older ages. However, forensic autopsy‐based data on workplace deaths in this population remain limited. This study aimed to evaluate the causes and manners of workplace‐related deaths among individuals aged 65 years and older ...
Muhammet Ali Oruç, Hüseyin Çağrı Şahin, Muhammed Oduncu, Muhammed Fatih Yaman, Abdulkadir Can   +4 more
wiley   +1 more source

When hoofbeats aren’t always horses: Hepatocellular carcinoma rupture in a Tuberculosis‐Endemic Context

Forensic Science International: Reports
Spontaneous rupture of hepatocellular carcinoma (HCC) is an uncommon cause of sudden death, particularly in non-cirrhotic individuals. We report a 59-year-old male who presented with one week of abdominal pain and died unexpectedly.
Yasmeen Abdhool, Lienke Perold
doaj   +1 more source

Preserving evidence integrity in full file system extractions: Assessing hash inconsistencies and potential solutions

Journal of Forensic Sciences, EarlyView.
Abstract Smartphone manufacturers' enhanced privacy and security measures, such as File‐Based Encryption (FBE), have disrupted traditional data extraction techniques, necessitating the adoption of Full File System Extraction (FFS). FFS requires booting a smartphone, decrypting its UserData partition, and accessing files individually, a process that ...
Sanghyun Yoo, Yunji Park, Doowon Jeong
wiley   +1 more source

Evaluation of illicit drug contaminants in seized cannabis in Arizona and California, 2023–2024

Journal of Forensic Sciences, EarlyView.
Abstract Despite public health concerns, fentanyl, cocaine, and other illicit drug contaminants remain largely understudied in unregulated cannabis. Here, we developed an analytical method to quantify a panel of common illicit drugs in cannabis and tested the law enforcement seizures in Arizona and California in evaluation of the illicit drug ...
Beckner Andersano, Thomas M. Cahill, Michael Grommes, Maxwell C. K. Leung   +3 more
wiley   +1 more source

Nosocomial Bacterial Bronchopneumonia and SARS-CoV-2 Pneumonia in Patients with Traumatic Injuries: Imaging Aspects and Macroscopic and Microscopic Findings of Lung Tissue

Diagnostics
Background: Patients with traumatic injuries often represent the best hosts for healthcare-associated infections, especially pneumonia or bronchopneumonia.
Georgiana-Denisa Gavriliţă, Ştefania Ungureanu, Ecaterina Dăescu, Mircea-Nicu Gavriliță, Cristian-Cosmin Ţîncu, Alexandra Enache   +5 more
doaj   +1 more source

From 15,000 to near zero: Cuyahoga County's eight‐year effort to address lawfully “owed” DNA

Journal of Forensic Sciences, EarlyView.
Abstract This study presents the final outcomes of an eight‐year, countywide initiative to address “lawfully owed” DNA (LODNA) among individuals who should have had a DNA sample in the Combined DNA Index System (CODIS) following a qualifying arrest or conviction but did not.
Rachel E. Lovell, Mary C. Weston, Duoduo Huang   +2 more
wiley   +1 more source