Results 101 to 110 of about 28,459 (282)

Developmental pathways to autism in tuberous sclerosis complex: Evidence from a longitudinal cohort

Epilepsia, EarlyView.
Abstract The association between autism spectrum disorder (hereafter referred to as autism) and tuberous sclerosis complex (TSC) is well established, yet the developmental pathways linking genetic mutation, cortical pathology, and epilepsy with autism remain unclear. The Tuberous Sclerosis 2000 Study recruited children newly diagnosed with TSC (N = 125)
Fiona S. McEwen, Abigail K. Runicles, Holan Liang, Emma Woodhouse, Lisa Underwood, Elizabeth Shephard, Edward D. Barker, Fintan Sheerin, Juul W. Steenbruggen, Tuberous Sclerosis 2000 Study Group, John R. W. Yates, Charlotte Tye, Patrick F. Bolton   +12 more
wiley   +1 more source

ER‐Localized Deadenylase PNLDC1 Suppresses Colorectal Cancer Progression by Targeting the mRNA Decay of TUBB4B

Exploration, EarlyView.
The deficiency of PNLDC1 exacerbates the advancement of CRC. PNLDC1 interacts with TUBB4B mRNA to regulate the p53–p21–CDK2–cyclin E2 pathway, thereby influencing the G2/M phase of the cell cycle. ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer‐related mortality, highlighting the urgent need for novel therapeutic strategies.
Lexin Liu, Yuelin Guan, Yuzhou Qin, Guiping Chen, Guozhen Wang, Xiang Yan, Xue Li, Lei Sun, Wei Yu, Shi Ouyang, Zhichao Ma, Zihao Xu, Zhongkai Cao, Fan Yu, Tong Zhou, Ziyou Luo, Xiangjun Chen, Yongbin Yan, Lidan Hu   +18 more
wiley   +1 more source

Polydatin alleviates adenine-induced nephropathy in mice

Renal Failure
Background Adenine-induced nephropathy (AIN) serves as a classic experimental model for studying uric acid-related renal injury, characterized by tubular obstruction, inflammatory cell infiltration, tubular epithelial cell apoptosis, and progressive ...
Tao Sheng, Tianhong Ma, Xin Jin, Debin Chen, Shipeng Che, Jie Wang, Jiadu Shen, Chaoqun Shi, Qiang Li, Yixin Sun, Deqing Chen, Guangtao Xu   +11 more
doaj   +1 more source

Applied surgical anatomical approach to pudendal nerve: Step‐by‐step key neurovascular structures for pelvic nerve surgery

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To define and demonstrate a step‐by‐step surgical anatomical approach to pudendal nerve dissection using female cadavers, focusing on the identification of safe roadmap and key neurovascular structures to optimize pelvic nerve surgery.
Merve Didem Eşkin Tanrıverdi, Ayhan Cömert, Zekiye Gözde Kara, Hasan Onur Topçu, Halil İbrahim Açar   +4 more
wiley   +1 more source

Paediatric Forensic Medicine and Pathology [PDF]

Journal of Clinical Pathology, 1990
openaire   +3 more sources

Structural Covariance Analysis of Altered Brain Development in Neonates With Congenital Heart Disease After Surgery

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Brain development is altered in neonates with congenital heart disease (CHD), with well‐characterised reductions in regional brain volumes and enlargement of CSF spaces. However, perioperative morphological changes remain incompletely understood. Purpose To identify brain regions showing spatial patterns of coordinated expansion and
Mirthe E. M. van der Meijden, Barat Gal‐Er, Benjamin Clayden, Siân Wilson, Daniel Cromb, Andrew T. M. Chew, Alexia Egloff, Kuberan Pushparajah, John Simpson, Joseph V. Hajnal, A. David Edwards, Mary Rutherford, Jonathan O'Muircheartaigh, Serena J. Counsell, Alexandra F. Bonthrone   +14 more
wiley   +1 more source

Legal Medicine in Italy

, 2017
The concept of Legai Medicine may refer to different activities in different countries. In Italy, a European country of Mediterranean tradition, Legai Medicine is a discipline which encompasses a plethora of topics and sub-disciplines: whereas for many ...
C. Cattaneo, R. Zoja
core   +2 more sources

Overview of the re‐evaluation of trace elements as nutritional feed additives in the European Union: characterization, safety, and efficacy

Journal of the Science of Food and Agriculture, EarlyView.
Abstract The re‐evaluation of feed additives in the European Union was outlined in the Regulation (EC) No 1831/2003. The primary objectives were to ensure safety and verify efficacy, as well as to update authorizations and phase out unsafe additives or those in which the industry expressed no interest.
Gloria López‐Gálvez, Maria de Lourdes Bastos, Francesco Cubadda, Mikolaj A Gralak, Christer Hogstrand, Matteo L Innocenti, Joop de Knecht, Marta López‐Alonso, Alberto Mantovani, Alena Pechová, Fernando Ramos, Jürgen Gropp   +11 more
wiley   +1 more source

Viral Pneumonias in Forensic Autopsies

, 2016
Lower respiratory infections are commonly due to viruses and are the third largest cause of death. Respiratory tract viruses have a tendency to target the specific regions in the lung and can harm the host via direct effect of the virus and the host's ...
Yildirim, Muzaffer, Asliyuksek, Hizir, Aytül Sargan, Ahmet Selçuk Gürler, Rifat Özdemirel, Topal, Cumhur Selcuk, Gurler, Ahmet Selcuk, Gülhan Yağmur, Taner Daş, Muzaffer Yildirim, Ozdemirel, Rifat, Das, Taner, Sargan, Aytul, Arslan, Murat Nihat, Yagmur, Gulhan, Hizir Asliyüksek, Cumhur Selçuk Topal, Murat Nihat Arslan   +17 more
core   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source