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Gene and pathway analysis of genome-wide genetic associations of bladder cancer. [PDF]
Curr UrolShi M, Meng X, Xu X, Wang Q.
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2022
Metabolic pathways are the foundation for understanding metabolomic data in its biochemical context. By mapping metabolomic results to these pathways and identifying those which are altered in the experiment, we can easily add biological interpretability to our experimental results.
Cavill, R., Bouwman, J.
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Metabolic pathways are the foundation for understanding metabolomic data in its biochemical context. By mapping metabolomic results to these pathways and identifying those which are altered in the experiment, we can easily add biological interpretability to our experimental results.
Cavill, R., Bouwman, J.
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A Relational Approach for Pathway Analysis
2008 International Multi-symposiums on Computer and Computational Sciences, 2008The relationship between interacting proteins can be represented using graphical network models. Comparison of models of similar protein networks can reveal important information about conserved protein interactions. The problem of determining conserved pathways between protein interaction networks are challenging and for large protein interaction ...
Cody Ashby +3 more
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Pathways to the analysis of microarray data
Trends in Biotechnology, 2005The development of microarray technology allows the simultaneous measurement of the expression of many thousands of genes. The information gained offers an unprecedented opportunity to fully characterize biological processes. However, this challenge will only be successful if new tools for the efficient integration and interpretation of large datasets ...
Curtis, R. Keira +3 more
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2019
Integrating prior knowledge of pathway-level information can enhance power and facilitate interpretation of gene expression data analyses. Here, we provide a practical demonstration of the value of gene set or pathway enrichment testing and extend such techniques to identify and characterize transcriptional subpopulations from single-cell RNA ...
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Integrating prior knowledge of pathway-level information can enhance power and facilitate interpretation of gene expression data analyses. Here, we provide a practical demonstration of the value of gene set or pathway enrichment testing and extend such techniques to identify and characterize transcriptional subpopulations from single-cell RNA ...
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An analysis of protein folding pathways
Biochemistry, 1991We have developed a model of the protein folding process based on three primary assumptions: that burying of hydrophobic area is the dominant contribution to the relative free energy of a conformation, that a record of the folding process is largely preserved in the final structure, and that the denatured state is a random coil.
J, Moult, R, Unger
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Lipidomic Analysis of Signaling Pathways
2007This chapter outlines methods that can be applied to determine the levels of lipids in cells and tissues. In particular, the methods focus upon the extraction and analysis of those lipids critical for monitoring signal transduction pathways. The methods address the analysis of the phosphoinositides, the lipid agonists lysophosphatidic acid and ...
Wakelam, Michael J.O. +2 more
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