Results 1 to 10 of about 7,950,605 (408)
European Psychiatry, 2023 Introduction COMP360 is a synthetic, proprietary, purified form of psilocybin in development for treatment-resistant depression (TRD) with FDA Breakthrough Therapy designation.
G. M. Goodwin +8 more
doaj +1 more source
KEGG for taxonomy-based analysis of pathways and genomes
Nucleic Acids Res., 2022 KEGG (https://www.kegg.jp) is a manually curated database resource integrating various biological objects categorized into systems, genomic, chemical and health information.
M. Kanehisa +4 more
semanticscholar +1 more source
The Complex Genetic and Epigenetic Regulation of the Nrf2 Pathways: A Review
Antioxidants, 2023 Nrf2 is a major transcription factor that significantly regulates—directly or indirectly—more than 2000 genes. While many of these genes are involved in maintaining redox balance, others are involved in maintaining balance among metabolic pathways that ...
Joe M. McCord +2 more
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Autophagy and autophagy-related pathways in cancer
Nature reviews. Molecular cell biology, 2023 Maintenance of protein homeostasis and organelle integrity and function is critical for cellular homeostasis and cell viability. Autophagy is the principal mechanism that mediates the delivery of various cellular cargoes to lysosomes for degradation and ...
Jayanta Debnath, Noor Gammoh, K. Ryan
semanticscholar +1 more source
Osteoarthritis: pathogenic signaling pathways and therapeutic targets
Signal Transduction and Targeted Therapy, 2023 Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects more than 500 million population worldwide. OA was believed to be caused by the wearing and tearing of articular cartilage, but it is now more commonly ...
Q. Yao +9 more
semanticscholar +1 more source
International Journal of Integrated Care, 2023 Introduction: Caring for patients with multimorbidity in general practice is increasing in amount and complexity. To integrate care for patients with multimorbidity and to support general practitioners (GPs), the Clinic for Multimorbidity (CM) was ...
Cathrine Bell +7 more
doaj +1 more source
Inflammation and tumor progression: signaling pathways and targeted intervention
Signal Transduction and Targeted Therapy, 2021 Cancer development and its response to therapy are regulated by inflammation, which either promotes or suppresses tumor progression, potentially displaying opposing effects on therapeutic outcomes.
Huakan Zhao +6 more
semanticscholar +1 more source
Scientific Reports, 2022 A major obstacle to tackling the growing burden of chronic disease in South Africa is lack of testing, particularly where individuals face multiple barriers to accessing health services.
Clara Calvert +4 more
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BMC Family Practice, 2020 Background Suspicion of deep vein thrombosis (DVT) is common and requires urgent and efficient investigation due to hazardous prognosis. The traditional diagnostic pathway can be complex and time-consuming, and innovative solutions may provide easy ...
Charlotte W. Appel +5 more
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BMC Cardiovascular Disorders, 2022 Background Left ventricular hypertrophy (LVH) is a marker of increased risk in developing future life-threatening cardiovascular disease (CVD), however, it is unclear how CVD risk factors, such as obesity, blood pressure (BP), and tobacco use, are ...
Andrea Kolkenbeck-Ruh +7 more
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