Results 141 to 150 of about 7,950,605 (408)
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source
A new scenario framework for climate change research: the concept of shared socioeconomic pathways
Climatic Change, 2014 The new scenario framework for climate change research envisions combining pathways of future radiative forcing and their associated climate changes with alternative pathways of socioeconomic development in order to carry out research on climate change ...
B. O’Neill +7 more
semanticscholar +1 more source
Pathways-driven Sparse Regression Identifies Pathways and Genes Associated with High-density Lipoprotein Cholesterol in Two Asian Cohorts [PDF]
arXiv, 2013 Standard approaches to analysing data in genome-wide association studies (GWAS) ignore any potential functional relationships between genetic markers. In contrast gene pathways analysis uses prior information on functional structure within the genome to identify pathways associated with a trait of interest. In a second step, important single nucleotide
arxiv
A Comparison of the Pathway Tools Software with the Reactome Software [PDF]
arXiv, 2020 This document compares SRI's Pathway Tools (PTools) software with the Reactome software. Both software systems serve the pathway bioinformatics area, including representation and analysis of metabolic pathways and signaling pathways. The comparison covers pathway bioinformatics capabilities, but does not cover other major facets of Pathway Tools that ...
arxiv
ChildrenBackground: Children with Down syndrome (DS) experience more difficulties with oral motor skills, including chewing, drinking, and swallowing. The present study attempts to measure the preliminary effectiveness of Global Intensive Feeding Therapy (GIFT ...
Silvia Franceschetti +7 more
doaj +1 more source
Journal of Clinical & Translational Endocrinology, 2014 Inhibitors of sodium-dependent glucose co-transporter 2 (SGLT2) increase glucose excretion in the urine and improve blood glucose in Type 2 diabetes mellitus. Glycosuria provides an energy and osmotic drain that could alter body composition. We therefore
Antonella Napolitano +6 more
doaj +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Ranking the importance of nuclear reactions for activation and transmutation events
, 2015 Pathways-reduced analysis is one of the techniques used by the Fispact-II nuclear activation and transmutation software to study the sensitivity of the computed inventories to uncertainties in reaction cross-sections. Although deciding which pathways are
Arter, Wayne +3 more
core +1 more source
ChildrenNecrotizing gingivitis (NG) is an acute inflammatory process with an estimated prevalence of less than 1%. The treatment of choice is usually antibiotics in addition to periodontal treatment.
Massimiliano Ciribè +7 more
doaj +1 more source
The prevalence of malnutrition and growth percentiles for urban South African children
BMC Public Health, 2019 Background Low- and middle-income countries (LMIC) are experiencing a double-burden of malnutrition characterised by high prevalence of both under- and over-nutrition.
Lukhanyo H. Nyati +2 more
doaj +1 more source