Results 21 to 30 of about 5,776,246 (295)

Total Lipopolysaccharide from the Human Gut Microbiome Silences Toll-Like Receptor Signaling

open access: yesmSystems, 2017
Cohabitation of microbial communities with the host enables the formation of a symbiotic relationship that maintains homeostasis in the gut and beyond. One prevailing model suggests that this relationship relies on the capacity of host cells and tissues ...
Eva d’Hennezel   +3 more
doaj   +1 more source

Education during the COVID-19: crisis Opportunities and constraints of using EdTech in low-income countries

open access: yesRED. Revista de Educación a Distancia, 2021
The Covid-19 pandemic has ushered in a period of educational disruption on an unprecedented scale. During this time of crisis, education will not be business as usual, and EdTech alone cannot close the learning gap.
Katy Jordan   +3 more
doaj   +1 more source

The representative concentration pathways: an overview

open access: yes, 2011
This paper summarizes the development process and main characteristics of the Representative Concentration Pathways (RCPs), a set of four new pathways developed for the climate modeling community as a basis for long-term and near-term modeling ...
D. P. Vuuren   +14 more
semanticscholar   +1 more source

Inflammation and atherosclerosis: signaling pathways and therapeutic intervention

open access: yesSignal Transduction and Targeted Therapy, 2022
Atherosclerosis is a chronic inflammatory vascular disease driven by traditional and nontraditional risk factors. Genome-wide association combined with clonal lineage tracing and clinical trials have demonstrated that innate and adaptive immune responses
Peng Kong   +5 more
semanticscholar   +1 more source

Converting acute inpatient take to outpatient take with fast-track assessment in internal medicine wards – a before-after study

open access: yesBMC Health Services Research, 2019
Background With an extensive rise in the number of acute patients and increases in both admissions and readmissions, hospitals are at times overcrowded and under immense pressure and this may challenge patient safety.
Cathrine Bell   +3 more
doaj   +1 more source

Signaling pathways involved in ischemic stroke: molecular mechanisms and therapeutic interventions

open access: yesSignal Transduction and Targeted Therapy, 2022
Ischemic stroke is caused primarily by an interruption in cerebral blood flow, which induces severe neural injuries, and is one of the leading causes of death and disability worldwide.
C. Qin   +9 more
semanticscholar   +1 more source

Metabolism pathways of arachidonic acids: mechanisms and potential therapeutic targets

open access: yesSignal Transduction and Targeted Therapy, 2021
The arachidonic acid (AA) pathway plays a key role in cardiovascular biology, carcinogenesis, and many inflammatory diseases, such as asthma, arthritis, etc.
Bei Wang   +8 more
semanticscholar   +1 more source

Signaling pathways and targeted therapy for myocardial infarction

open access: yesSignal Transduction and Targeted Therapy, 2022
Although the treatment of myocardial infarction (MI) has improved considerably, it is still a worldwide disease with high morbidity and high mortality.
Qing Zhang   +10 more
semanticscholar   +1 more source

Targeted proteomics of appendicular skeletal muscle mass and handgrip strength in black South Africans: a cross-sectional study

open access: yesScientific Reports, 2022
Although appendicular skeletal muscle mass (ASM) and handgrip strength (HGS) are key components of sarcopenia, their underlying biological mechanisms remain poorly understood.
Siphiwe N. Dlamini   +7 more
doaj   +1 more source

Navigating relationship dynamics, pregnancy and fatherhood in the Bukhali trial: a qualitative study with men in Soweto, South Africa

open access: yesBMC Public Health, 2023
Background South Africa has a complex range of historical, social, political, and economic factors that have shaped fatherhood. In the context of the Bukhali randomised controlled trial with young women in Soweto, South Africa, a qualitative study was ...
Catherine E. Draper   +8 more
doaj   +1 more source

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