Results 61 to 70 of about 5,776,246 (295)
International Journal of Behavioral Nutrition and Physical Activity, 2022 Background Relationships between mental health and multiple health behaviours have not been explored in young South African women experiencing social constraints.
Catherine E. Draper +8 more
doaj +1 more source
The MetaCyc database of metabolic pathways and enzymes - a 2019 update
Nucleic Acids Res., 2019 MetaCyc (MetaCyc.org) is a comprehensive reference database of metabolic pathways and enzymes from all domains of life. It contains 2749 pathways derived from more than 60 000 publications, making it the largest curated collection of metabolic pathways ...
R. Caspi +9 more
semanticscholar +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
International Journal of Integrated CareIntroduction: Patients with multiple autoimmune diseases lack continuity of care due to increasing specialisation and siloed practice in healthcare. Despite improvements in quality, this organisation has led to fragmented patient pathways, as related ...
Sarah Holm Junge Jensen +7 more
doaj +1 more source
Non-homologous DNA end joining and alternative pathways to double-strand break repair
Nature reviews. Molecular cell biology, 2017 DNA double-strand breaks (DSBs) are the most dangerous type of DNA damage because they can result in the loss of large chromosomal regions. In all mammalian cells, DSBs that occur throughout the cell cycle are repaired predominantly by the non-homologous
Howard H. Y. Chang +3 more
semanticscholar +1 more source
Understanding MAPK Signaling Pathways in Apoptosis
International Journal of Molecular Sciences, 2020 MAPK (mitogen-activated protein kinase) signaling pathways regulate a variety of biological processes through multiple cellular mechanisms. In most of these processes, such as apoptosis, MAPKs have a dual role since they can act as activators or ...
Jicheng Yue, José M. López
semanticscholar +1 more source
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
The South African Journal of Clinical NutritionBackground Non-communicable diseases are the leading cause of deaths across the globe and low-to-middle income countries (LMICs) are disproportionally affected.
A Craig +4 more
doaj +1 more source
Epidermal Growth Factor Receptor Cell Proliferation Signaling Pathways
Cancers, 2017 The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase that is commonly upregulated in cancers such as in non-small-cell lung cancer, metastatic colorectal cancer, glioblastoma, head and neck cancer, pancreatic cancer, and breast ...
Ping Wee, Zhixiang Wang
semanticscholar +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source