Results 121 to 130 of about 78,269 (301)

Establishing Sensory Neurons as Therapeutic Targets in Peripheral Neuropathy Driven by Polyglutamine Expanded Murine ATXN3

Annals of Neurology, EarlyView.
Repeat expansion disorders frequently involve peripheral neuropathy, yet mechanisms remain unclear. Using a spinocerebellar ataxia type 3 (SCA3) Knock‐In Atxn3Q300/Q6, we identify progressive sensorimotor deficits, peripheral nerve pathology, and dorsal root ganglia RNA splicing dysregulation.
Juan P. Mato, John M. Hayes, Jacen Emerson, Maeha Sridharan, Toluwani Adelaja, Arsal Naeem, Alexandra F. Putka, Hayley S. McLoughlin   +7 more
wiley   +1 more source

The Comparison of Preemptive Oral Tramadol, Gabapentin Tramadol and Parasetamol Tramadol Combination on the Efficacy of Postoperative Pain Control in Breast Reduction Surgery

Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2013
Purpose: Application of tramadol by intravenous patient controlled analgesia (PCA) is a routine method for controlling postoperative pain in the breast reduction operations.
Muge Can, Zehra Hatipoglu, Cengiz Eser, Yasemin Gunes   +3 more
doaj  

Postoperative Patient-controlled Analgesia: Thirty Years of Clinical Experience in Peking Union Medical College Hospital

Xiehe Yixue Zazhi
Postoperative pain seriously affects the recovery process of patients, resulting in prolonged hospital stay and increased care costs. Appropriate application of patient-controlled analgesia devices can effectively relieve perioperative acute pain.
ZHAO Lin, REN Liying, NIE Weihua, CHEN Yaqi, ZHANG Jie, ZHANG Shengjie, WANG Yingli, DIAO Cuicui, MA Huiying, ZHANG Zheng, ZHOU Li, SHEN Le, WANG Huizhen, HUANG Yuguang   +13 more
doaj   +1 more source

Design Considerations for Polymer–Deep Eutectic Solvent Hybrid Systems for Transdermal Drug Delivery

Journal of Applied Polymer Science, EarlyView.
Deep eutectic solvents (DESs) act as tunable, green excipients that modulate polymer structure–property relationships to enhance drug solubility, skin permeation, stability, and controlled release. Through hydrogen‐bond interactions, DES–polymer hybrid systems enable improved transdermal performance, offering a rational, design‐driven platform for ...
Madhavi Kailas Kapale, Madhur Kulkarni, Pranav J. Shah, Furqan A. Maulvi   +3 more
wiley   +1 more source

Magnetic Resonance Imaging Modified Dixon Fat Quantification Analysis Is a Quantitative and Reliable Method for Evaluating Fatty Atrophy of the Hamstring Muscle Complex After Proximal Avulsion Injury

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To evaluate the reliability and validity of objective fat quantification using the modified Dixon magnetic resonance imaging sequence for assessing fatty degeneration in conservatively treated patients with proximal hamstring avulsion injuries. Methods Magnetic resonance imaging with modified Dixon sequence was used.
John Hanke, Philipp Schenk, Irga Kemal, Markus Heinecke, Philipp Kobbe, Thomas Mendel   +5 more
wiley   +1 more source

The Effects of Tramadol and Levobupivacaine Infiltration on Postoperative Analgesia in Functional Endoscopic Sinus Surgery and Septorhinoplasty

Balkan Medical Journal, 2012
Objective: The aim of this prospective, randomized, double-blind study was to investigate the postoperative analgesic effects of levobupivacaine or tramadol infiltration administered prior to surgery in septorhinoplasty (SRP) or endoscopic sinus surgery (
Gökşen Öz, Alparslan Apan, Muhammet Hilmi Koputan, Emine Arzu Köse   +3 more
doaj  

Anterior Knee Unloader Brace Prescription Yields Moderate Compliance Rates and Improved Clinical Function in Patients with Patellofemoral Pain

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To determine clinical outcome changes and wear compliance rates associated with the use of a custom‐fit anterior knee unloader brace in a prospective cohort of patients with clinical symptoms derived from patellofemoral osteoarthritis (PFOA).
Andrew R. Phillips, Thomas Moran, Kofi K. Acheampong, Stephanie A. Boden, Erik C. Haneberg, William D. Bugbee, John P. Fulkerson, Simon Goertz, John G. Lane, Sabrina M. Strickland, Adam B. Yanke   +10 more
wiley   +1 more source

Patient-controlled analgesia for burn patients: a preliminary report [PDF]

, 1988
The introduction of patient-controlled analgesia for burn patients is reported. It has been used for 18 postoperative patients and five patients with acute thermal injury. The system has been found to be easy to use.
Glavin, R., Kinsella, J., Reid, W.H.
core  

A Multicenter, Open‐Label, Phase 2 Trial Comparing Crizanlizumab Combined With Standard Therapy to Standard Therapy Alone on Renal Function in Patients With Sickle Cell Nephropathy (STEADFAST)

American Journal of Hematology, EarlyView.
Kenneth I. Ataga, Pablo Bartolucci, Santosh L. Saraf, Vimal K. Derebail, Adlette Inati, Jeffrey D. Lebensburger, Laurie DeBonnett, Rodolfo D. Cancado, Claire C. Sharpe   +8 more
wiley   +1 more source

Perioperative Intravenous Dexamethasone Improves Pain and Functional Outcomes After Arthroscopic Rotator Cuff Repair

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To evaluate the effect of perioperative dexamethasone on patient‐reported pain, functional outcomes, and minimal clinically important difference (MCID) achievement following arthroscopic rotator cuff repair. Methods Patients who underwent rotator cuff repair between 2013 and 2023 were identified and divided into groups.
Trevor D. Wolterink, Germain Craddock, Joshua P. Castle, Michael A. Gaudiani, Chimdindu Obinero, Alexander S. Jurayj, Christian A. Freitag, Nathan Y. Li, Jared Mahylis, Stephanie J. Muh   +9 more
wiley   +1 more source