Results 81 to 90 of about 169,466,874 (244)

Dutch GP healthcare consumption in COVID-19 heterogeneous regions: an interregional time-series approach in 2020–2021

BJGP Open
Background: Many countries observed a sharp decline in the use of general practice services after the outbreak of the COVID-19 pandemic. However, research has not yet considered how changes in healthcare consumption varied among regions with the same ...
Maarten Homburg, Marjolein Berger, Matthijs Berends, Eline Meijer, Thijmen Kupers, Lotte Ramerman, Corinne Rijpkema, Evelien de Schepper, Tim olde Hartman, Jean Muris, Robert Verheij, Lilian Peters   +11 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

The association of oral health knowledge with the behavior of pregnant women visiting the dentist based on the theory of planned behavior: Cross-sectional studies

Padjadjaran Journal of Dentistry
Introduction: A lack of knowledge of oral health maintenance among pregnant women affects the behavior of maintaining poor oral health.  It is important for pregnant women to visit the dentist due to their increased susceptibility to oral diseases, which
Dikkara Rizqi, Netty Suryanti, Anne Agustina Suwargiani, Niekla Survia Andiesta   +3 more
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Barriers to treatment: describing them from a different perspective

Patient Preference and Adherence, 2018
Francesca Devine,1 Taylor Edwards,1 Steven R Feldman1–3 1Center for Dermatology Research, Department of Dermatology, 2Department of Pathology, 3Department of Social Sciences & Health Policy, Wake Forest School of Medicine, Winston-Salem, NC ...
Devine F, Edwards T, Feldman SR
doaj  

Managerial practices for app-based primary care telemedicine service acceptance in South Africa

South African Journal of Business Management
Purpose: This study addresses the qualitative research phase of a mixed methods study conducted to investigate patient acceptance of an app-based telemedicine service for primary care aimed at South African public health care sector patients.
Grethe van Tonder, Ronel du Preez, Christian D. Pentz   +2 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Key Information Influencing Patient Decision-Making About AI in Health Care: Survey Experiment Study

Journal of Medical Internet Research
BackgroundArtificial intelligence (AI)–enabled devices are increasingly used in health care. However, there has been limited research on patients’ informational preferences, including which elements of AI device labeling enhance patient understanding ...
Xuan Zhu, Austin M Stroud, Sarah A Minteer, Dong Whi Yoo, Jennifer L Ridgeway, Maryam Mooghali, Jennifer E Miller, Barbara A Barry   +7 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source