Results 121 to 130 of about 6,814,812 (297)

Is patient-centredness in European hospitals related to existing quality improvement strategies? Analysis of a cross-sectional survey (MARQuIS study). [PDF]

, 2009
BACKGROUND: There is growing recognition of patients' contributions to setting objectives for their own care, improving health outcomes and evaluating care.
Lombarts, MJMH, Klazinga, N., Groene, O., Groene, O, Thompson, A, Lombarts, M.J.M.H., Lombarts, M. J. M. H., Klazinga, N, Suñol, R, Suñol, R., Groene, Oliver, Suñol Sala, Rosa, Alonso, J., Alonso, J, Thompson, A.   +14 more
core   +2 more sources

Evidence-based patient choice: a prostate cancer decision aid in plain language

BMC Medical Informatics and Decision Making, 2005
Background Decision aids (DA) to assist patients in evaluating treatment options and sharing in decision making have proliferated in recent years. Most require high literacy and do not use plain language principles.
Ohene-Frempong Janet, Dunn Rodney L, Wei John T, Fagerlin Angela, Stableford Sue, Holmes-Rovner Margaret, Kelly-Blake Karen, Rovner David R   +7 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Study protocol: Improving patient choice in treating low back pain (IMPACT - LBP): A randomised controlled trial of a decision support package for use in physical therapy [PDF]

, 2011
Copyright @ 2011 Patel et al - This is an Open Access article distributed under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any ...
Tysall, C, Brown Sally, Thistlethwaite, J, Tim Friede, Griffiths Frances, Woolvine, Mark, Underwood, Martin, Tysall, C., Martin Underwood, Thistlethwaite, Jill, Lord, J, Sally Brown, Joanne Lord, Colin Tysall, Underwood Martin, Underwood, M, Woolvine, M., Woolvine Mark, Brown, S, Brown, S., Ngunjiri Anne, Shilpa Patel, Jill Thistlethwaite, Woolvine, M, Friede, T, Underwood, M., Ngunjiri, A., Ngunjiri, Anne, Griffiths, F., Tysall, Colin, Anne Ngunjiri, Friede, T., Griffiths, F, Thistlethwaite, J., Ngunjiri, A, Friede Tim, Frances Griffiths, Patel, Shilpa, Lord, J., Thistlethwaite Jill, Mark Woolvine, Lord Joanne, Lord, Joanne, Friede, Tim, Tysall Colin, Patel, S, Brown, Sally, Patel Shilpa, Griffiths, Frances, Patel, S.   +49 more
core   +2 more sources

Development and pilot testing of the Population And ContExt adaption of decision aids (PACE) framework

PEC Innovation
Objective: This study aimed to develop and pilot test a new framework for the adaptation of patient decision aids (PtDAs) using a specific case example of contraceptive method PtDAs for Chinese-speaking migrant women.
Hankiz Dolan, Deborah Bateson, Mu Li, Rachel Thompson, Chun Wah Michael Tam, Carissa Bonner, Lyndal Trevena   +6 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Have a vital end-user been overlooked? Developing a shared decision intervention for patients with potential pancreatic cancer regarding the choice of surgery

PEC Innovation
Objective: To develop a patient decision aid facilitating shared decision making for patients with potential pancreatic cancer deciding about no treatment, surgical or medical treatment.
Kristine Elberg Dengsø, Anne Berg, Carsten Palnæs Hansen, Stefan K. Burgdorf, Paul S. Krohn, Martin Sillesen, Nina Spiegelhauer, Mette Tholstrup Bach, Marianne Melton, Betina Nielsen, Bo Marcel Christensen, Jeanette Finderup, Jens Hillingsø   +12 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Patient safety in health care professional educational curricula: examining the learning experience [PDF]

, 2009
This study has investigated the formal and informal ways pre-registration students from four healthcare professions learn about patient safety in order to become safe practitioners.
Steven, Alison, Pearson, Pauline, Dawson, Pam   +2 more
core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source