Results 101 to 110 of about 6,814,812 (297)

Design a decision-making aid: "alternative treatment for prostate cancer: what option do you prefer?"

Psicooncologia, 2010
Purpose: To design a Decision-making Aid within the ‘Benign Prostatic Hyperplasia’ healthcare process modelling of the Andalusian Public Health System (SSPA) for the therapeutic approach of early-stage disease.
Carmen Pérez, Enrique Alonso, Guadalupe Carmona, Araceli Caro, José Luis Padilla, Víctor Baena, Francisco J. Torrubia, María Josefa Requena, Ismael Herruzo, Ramón Linares, Reyes Sanz, José Luis Soler, Pedro Pablo Pérez, Juan Carlos Villalobos   +13 more
doaj  

Decision aids in patients with osteoporosis: A scoping review

PLOS One
Introduction Although various methods exist for osteoporosis prevention, most patients fail to receive optimal treatment due to information asymmetry between physicians and patients, as well as limited consultation time. Current literatures suggest that decision aids can support clinical decision-making by improving patients’ risk perception and ...
Yanyu Fang, Qin Jia, Yaqin Dai, Siqi Li
openaire   +4 more sources

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Design and development of a decision aid to enhance shared decision making by patients with an asymptomatic abdominal aortic aneurysm

, 2008
Dirk T Ubbink1,2, Anouk M Knops1, Sjaak Molenaar1, Astrid Goossens11Department of Quality Assurance and Process Innovation and 2Department of Surgery, Academic Medical Center, Amsterdam, The NetherlandsObjective: To design, develop, and evaluate an ...
Astrid Goossens, Knops, Anouk M., Goossens, Astrid, Molenaar, Sjaak, Dirk T Ubbink, Ubbink, Dirk T., Anouk M Knops, Sjaak Molenaar   +7 more
core  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Shared decision‐making and the use of patient decision aids [PDF]

Prescriber, 2016
As part of our series on the NICE Medicines Optimisation guideline, 1 this article discusses the section of the guidance concerning shared decisionmaking and the use of patient decision aids.
openaire   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Development of a patient decision aid for type 2 diabetes mellitus for patients not achieving glycemic control on metformin alone

, 2015
Alicia C Shillington,1 Nananda Col,2 Robert A Bailey,3 Mark A Jewell11EPI-Q, Inc., Oak Brook, IL, USA; 2Shared Decision-making Resources, Georgetown, ME, USA; 3Janssen Scientific Affairs, LLC, Raritan, NJ, USAPurpose: To describe the process used to ...
Shillington AC, Col N, Jewell MA, Bailey RA   +3 more
core  

Impact of timing and format of patient decision aids for breast cancer patients on their involvement in and preparedness for decision making - the IMPACTT randomised controlled trial protocol

BMC Cancer
Background After curative surgery for early-stage breast cancer, patients face a decision on whether to undergo surgery alone or to receive one or more adjuvant treatments, which may lower the risk of recurrence. Variations in survival outcomes are often
Bettina Mølri Knudsen, Stine Rauff Søndergaard, Dawn Stacey, Karina Dahl Steffensen   +3 more
doaj   +1 more source