Results 41 to 50 of about 1,033,011 (354)

Disposition and Success of Patients Following Discharge in the Acute Setting

, 2017
: Background & Purpose: Many patients are seen in the hospital by physical therapists who also help decide where the patient will go after discharge (e.g., home, rehab hospital, skilled nursing facility) with the goal being the safest and best quality of
Cortney, Ciera, Lutjens, Kathryn, Raines, Kristopher   +2 more
core   +1 more source

Bridges and Barriers: Patients\u27 Perceptions of the Discharge Process Including Multidisciplinary Rounds on a Trauma Unit [PDF]

, 2015
Discharge planning is a complex process and ideally begins early in the patient stay. Despite evidence about the importance of discharge readiness, there is limited literature about the patient\u27s view during this transition. The goal of this study was
Johnson, Grace, Klink, Katie, Mcandrew, Natalie S., Schroeter, Kathryn, Zakzesky, Dawn   +4 more
core   +1 more source

Variations in follow-up services after inpatient stroke rehabilitation: A multicentre study [PDF]

, 2009
Background: Care after discharge from inpatient stroke rehabilitation units varies across Europe. The aim of this study was to compare service delivery after discharge.
Baert, Ilse, Brinkmann, Nadine, De Weerdt, Willy, De Wit, Liesbet, Dejaeger, Eddy, Feys, Hilde, Jenni, Walter, Kaske, Christiane, Leys, Mark, Lincoln, Nadina, Louckx, Fred, Putman, Koen, Schuback, Birgit, Schupp, Wilfried, Smith, Bozena   +14 more
core   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Patients’ Perceptions of Relative Importance of Discharge Elements (PRIDE) Study [PDF]

, 2019
Background: Almost 20% of patients experience potentially preventable adverse events within 30 days of hospital discharge (Forster, et al, 2003). The Agency for Healthcare Research and Quality recommends structured and patient-centered discharge ...
Kurbanova, Nargiza
core   +1 more source

Physical outcome measure for critical care patients following intensive care discharge [PDF]

, 2016
Introduction: The aim of this study was to evaluate the most suitable physical outcome measures to be used with critical care patients following discharge. ICU survivors experience physical problems such as reduced exercise capacity and intensive care
Daniel, M, Devine, H, Kinsella, J., MacTavish, P, McPeake, J., Quasim, T.   +5 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Early Ambulation Shortened the Length of Hospital Stay in ICU Patients after Abdominal Surgery

Clinics and Practice, 2023
The optimal time to ambulation remains unclear for intensive care unit (ICU) patients following abdominal surgery. While previous studies have explored various mobilization techniques, a direct comparison between ambulation and other early mobilization ...
Takashi Amari, Daiki Matta, Yukiho Makita, Kyosuke Fukuda, Hiroki Miyasaka, Masami Kimura, Yuta Sakamoto, Satoshi Shimo, Kenichiro Yamaguchi   +8 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source