Results 91 to 100 of about 2,063,671 (406)
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi+5 more
wiley +1 more source
Practical Strategies for Pharmacist Integration with Primary Care: A Workbook. [PDF]
This workbook is a practical set of tips and resources to assist pharmacists in providing clinical pharmacy services to primary care providers and their patients.
Biddle, Michael A, Kennedy, Amanda G
core +1 more source
Clinical Practice Guidelines for Recall and Maintenance of Patients with Tooth-Borne and Implant-Borne Dental Restorations [PDF]
Purpose To provide guidelines for patient recall regimen, professional maintenance regimen, and at-home maintenance regimen for patients with tooth-borne and implant-borne removable and fixed restorations.
Bidra, Avinash S.+9 more
core +2 more sources
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane+16 more
wiley +1 more source
Las infecciones de transmisión sexual (ITS) se han convertido en una amenaza para la vida de millones de personas en un corto período de tiempo, por lo que deben tomarse las medidas necesarias por las entidades encargadas para alejar esa amenaza.
Roilmer Rodríguez Lores+4 more
doaj
Extracting Topics from Open Educational Resources [PDF]
In recent years, Open Educational Resources (OERs) were earmarked as critical when mitigating the increasing need for education globally. Obviously, OERs have high-potential to satisfy learners in many different circumstances, as they are available in a wide range of contexts.
arxiv
The colliding epidemics of non-communicable diseases including diabetes with chronic infectious diseases in Sub-Saharan Africa requires contextualized innovative disease management strategies.
T. Masupe+6 more
semanticscholar +1 more source
How medical students demonstrate their professionalism when reflecting on experience [PDF]
Objectives: This paper aims to examine the discourses used by students in a formal assessment of their ability to demonstrate professional values when reflecting on their experiences. Methods: We carried out a discourse analysis of 50 randomly selected
Ainsworth+27 more
core +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source
Supervised multi-specialist topic model with applications on large-scale electronic health record data [PDF]
Motivation: Electronic health record (EHR) data provides a new venue to elucidate disease comorbidities and latent phenotypes for precision medicine. To fully exploit its potential, a realistic data generative process of the EHR data needs to be modelled. We present MixEHR-S to jointly infer specialist-disease topics from the EHR data.
arxiv