Results 81 to 90 of about 521,278 (295)

Quality of Dietetic Patient Education Materials for Diabetes and Gastrointestinal Disorders: Where Can We Do Better?

Dietetics
(1) Background: Patient education materials are frequently used by dietitians to support counselling and reinforce key concepts. No studies have examined the quality of dietetic patient education materials for diabetes and common gastrointestinal ...
Kelly Lambert, Olivia Hodgson, Claudia Goodman   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

A critical readability and quality analysis of internet‐based patient information on neck dissections

World Journal of Otorhinolaryngology-Head and Neck Surgery, 2023
Objective Patients are increasingly turning to the Internet as a source of healthcare information. Given that neck dissection is a common procedure within the field of Otolaryngology ‐ Head and Neck Surgery, the aim of this study was to evaluate the ...
Elysia M. Grose, Joo Hyun Kim, Justine Philteos, Marc Levin, Jong Wook Lee, Eric A. Monteiro   +5 more
doaj   +1 more source

Evaluation of Readability in Patient Education Materials for Primary Hyperparathyroidism

Patient education is essential for effective medical care. Although over half of patients search for health information online, most educational materials exceed the recommended sixth-grade reading level.
Vaghaiwalla, Tanaz M, Grabeel, Kelsey L, Nikbakht, Amirreza, Armstrong, Valerie L, Murdock, Peyton, Lew, John I, Heidel, R Eric   +6 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

What should lung cancer patients know before surgery? A Delphi consensus studyCentral MessagePerspective

JTCVS Open
Objective: Preoperative patient education improves surgical outcomes but high variability of existing patient education materials (PEMs) exists. This study establishes thoracic surgeon consensus on essential content included in PEMs to help patients to ...
Woorin Jang, BS, Mark K. Ferguson, MD, Mara Antonoff, MD, Mark Block, MD, Malcolm DeCamp, Jr., MD, Elisabeth Dexter, MD, Jessica Donington, MD, MSCR, Melanie Edwards, MD, Crystal Erickson, MD, David Tyler Greenfield, MD, Eric L. Grogan, MD, MPH, Jeffrey Hagen, MD, Matthew L. Inra, MD, Jody Kaban, MD, Peter J. Kneuertz, MD, Sean Kwon, MD, Geoffrey Lam, MD, Keith Mortman, MD, Keith Naunheim, MD, Brian Pettiford, MD, Daniel P. Raymond, MD, Janani S. Reisenauer, MD, R. Taylor Ripley, MD, Lary Robinson, MD, Christopher W. Seder, MD, Harmik Soukiasian, MD, Ruchi Thanawala, MD, Nakul Valsangkar, MBBS, Nirmal Veeramachaneni, MD, Jason Wallen, MDCM, Thomas Watson, MD, Ory Wiesel, MD, Maria Lucia L. Madariaga, MD   +32 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Readability of Online Patient Education Materials for Dental Radiology

, 2021
Background: Dental patients may seek and read online patient education materials pertaining to dental radiology. Objective: The objective of this study was to quantitatively evaluate the readability of online patient education materials pertaining to ...
Yeung, AWK
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Microbial foodborne illnesses in Bahrain: a strategy to empower the community, enhance the environment and improve resources to control such hazards [PDF]

This descriptive study was conducted in the State of Bahrain using: firstly, a questionnaire for students in the final year of their school education, together with a similar questionnaire for their parents, teachers and all Bahraini health promoters ...
Ali, Abdulla Ahmed
core