Results 91 to 100 of about 1,106,363 (300)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Patient education materials: improving readability to advance health equity
Journal of Perinatal MedicineTo assess the readability of American College of Obstetricians and Gynecologists (ACOG) patient education pamphlets and evaluate changes over 25 years to determine their role as a social determinant of health affecting maternal health disparities.
Grünebaum Amos +4 more
doaj +1 more source
Educational material for the patient with leprosy
Leprosy Review, 1989 This paper addresses the need for suitably written and illustrated material for the patient with leprosy with emphasis on the effective administration of WHO recommended multiple drug therapy (MDT) and the prevention of deformities. The successful implementation of MDT strategy for leprosy control calls for attention to a package of activities, amongst
A C, McDougall, G D, Georgeiv
openaire +2 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
A Layered Approach to Understanding Your Patient: A Tool for Patient Education
MedEdPORTAL, 2013 Patient education encompasses more than just telling a patient to read materials; it is a process of working with a patient to promote behavioral change.
Jill Stefaniak
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, 1996 Alumni publication of the Boston University School of Dental ...
Office of External Affairs, Boston University Goldman School of Dental Medicine
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
MedEdPORTAL, 2015 This educational tool kit has been developed for health professional learners to provide instruction on patient education practices in health care as well as to engage learners in designing patient education tools.
Christopher AhnAllen, DeAnna Mori
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