Results 141 to 150 of about 3,496,462 (296)

Developing and Implementing a Narration of Care Framework to Teach Nurses When and How to Narrate Care

Nursing Reports
Background: It is generally well-known that narration of care is critically important to high-quality nursing care. Narration of care is loosely defined as a nurse’s ability to describe to patients and families the clinical purpose behind nursing ...
Courtenay R. Bruce, Natalie N. Zuniga-Georgy, Nathan Way, Lenis Sosa, Emmanuel Javaluyas, Terrell L. Williams, Gail Vozzella   +6 more
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Field observation as a method to guide patient-reported outcome measurement integration in community cancer centers

Implementation Science Communications
Background Field observation is a valuable but underused methodological approach in patient-reported outcomes (PRO) implementation research, particularly in low-resourced settings such as community cancer centers (CCCs). Rooted in ethnographic tradition,
Manraj N. Kaur, Amanda Higgins, Maria O. Edelen, Kelly A. Aschbrenner, Meghan E. Garstka, Alyssa Throckmorton, Vivian Bea, Andrea L. Pusic   +7 more
doaj   +1 more source

US food allergy patients’ experiences, priorities, and needs: A qualitative study

Journal of Allergy and Clinical Immunology: Global
Background: Understanding patient experiences with food allergies (FAs) is essential for developing treatments that meet patients’ needs and aiding clinicians in optimizing care.
Elisabeth Oehrlein, MS, PhD, Silke C. Schoch, MA, Omar A. Escontrías, DrPH, MPH, Melanie Carver, AS, Sanaz Eftekhari, BA, Jessica Marvel, MPH, Chris Leo Pashos, PhD, Michael Pistiner, MD, MMSc, Randall Rutta, MA, Jill Voss, BSc Hons, MSc, Joe Vandigo, MBA, PhD   +10 more
doaj   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Implementation and Evaluation of the RECAP Framework: A Quality Improvement Initiative

Nursing Reports
Background: Narration of care (NOC) refers to a nurse’s ability to explain the purposes, goals, and objectives of nursing tasks. In this project, narration of care (NOC) refers to real-time verbal explanation of nursing tasks and should not be confused ...
Courtenay R. Bruce, Natalie N. Zuniga-Georgy, Nathan Way, Lenis Sosa, Emmanuel Javaluyas, Terrell L. Williams, Swetha Mulpur, Gail Vozzella   +7 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source